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LEF1 Produkte

(Lymphoid Enhancer-Binding Factor 1 (LEF1))

Kategorien

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

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Ausgewählte LEF1 Kategorien

LEF1 Antikörper

High quality antibodies with extensive validation data.

LEF1 ELISA Kits

Reliable ELISA kits for a wide range of species.

LEF1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene LEF1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (6)
  • (1)
Kat. Nr. ABIN5663810
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
  • (6)
Kat. Nr. ABIN735248
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, RNAi
Validierungen
  • (2)
  • (6)
Kat. Nr. ABIN565556
Menge 100 μg
Datenblatt Datenblatt

Empfohlene LEF1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6219167
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6219163
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6219160
Menge 96 tests
Datenblatt Datenblatt

Empfohlene LEF1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1309292
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123803
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1309296
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren LEF1 Produkten

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Zambanini, Nordin, Jonasson, Pagella, Cantù: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).

Fu, Huang, Wang, Chen, Huang, Lu, Liang, Zhang: "Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development." in: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).

Xu, Zhao, Zhang, Xu, Yang, Wang, Liu: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/?-catenin Signaling in Lungs of Neonatal Rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).

Wang, Xie, Xie, Wan, Ma, Qi, Yang: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).

Yao, Li, Liang, Lu, Zhu, Liu, Zhang, Yuan, Wang: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).

Song, Man, Wang, Bai, Wei, Liu, Liu, Gu, Wang: "The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of ?-Catenin Following Tail Amputation." in: Journal of molecular neuroscience : MN, (2014) (PubMed).

Shimomura, Takasaki, Nomura, Hayashi, Senda: "Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1." in: Medical molecular morphology, Vol. 46, Issue 1, pp. 14-9, (2013) (PubMed).

Jamieson, Sharma, Henderson: "Regulation of ?-catenin nuclear dynamics by GSK-3? involves a LEF-1 positive feedback loop." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 8, pp. 983-99, (2011) (PubMed).

Gutierrez, Tschumper, Wu, Shanafelt, Eckel-Passow, Huddleston, Slager, Kay, Jelinek: "LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis." in: Blood, Vol. 116, Issue 16, pp. 2975-83, (2010) (PubMed).

Synonyme und alternative Namen zu LEF1

lymphoid enhancer binding factor 1 (LEF1), lymphoid enhancer binding factor 1 (lef1), lymphoid enhancer-binding factor 1 (lef1), lymphoid enhancer binding factor 1 (Lef1), lymphoid enhancer factor XLEF-1B (lef1), 3000002B05, AI451430, Lef-1, LEF-1, LEF1, TCF1ALPHA, TCF7L3, TCF10

Bezeichner auf Proteinebene für LEF1

  • lymphoid enhancer binding factor-1
  • lymphoid enhancer-binding factor 1
  • lymphoid enhancer-binding factor 1-like
  • etID310027.1
  • LEF-1
  • lymphoid enhancer binding factor 1 short isoform
  • T cell-specific transcription factor 1-alpha
  • TCF1-alpha
  • lymphiod enhancer binding factor 1
  • transcription factor LEF-1
  • lymphoid enhancer binding factor 1
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