Left-Right Determination Factor Produkte
(Left-Right Determination Factor (LEFTY-A))
Kategorien
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010].
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Ausgewählte Left-Right Determination Factor Kategorien
Left-Right Determination Factor Antikörper
High quality antibodies with extensive validation data.
Empfohlene Left-Right Determination Factor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, ELISA, IHC, IP, RIA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN103459
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
Kat. Nr.
ABIN5623568
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
Kat. Nr.
ABIN1983337
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Left-Right Determination Factor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4883592
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6386359
Menge
96 tests
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Left-Right Determination Factor Produkten
: "Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21397-404, (2001) (PubMed).: "Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11376-81, (1999) (PubMed).
: "lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal." in: Cell, Vol. 94, Issue 3, pp. 287-97, (1998) (PubMed).
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