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LIFR Produkte

(Leukemia Inhibitory Factor Receptor alpha (LIFR))
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5\;8)(p13\;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte LIFR Kategorien

LIFR Antikörper

High quality antibodies with extensive validation data.

LIFR ELISA Kits

Reliable ELISA kits for a wide range of species.

LIFR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene LIFR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7437698
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7437992
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7432040
Menge 100 μL
Datenblatt Datenblatt

Empfohlene LIFR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (6)
Kat. Nr. ABIN6730977
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968279
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957463
Menge 96 tests
Datenblatt Datenblatt

Empfohlene LIFR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275152
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275153
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN2444162
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren LIFR Produkten

Worzfeld, Finkernagel, Reinartz, Konzer, Adhikary, Nist, Stiewe, Wagner, Looso, Graumann, Müller: "Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 2, pp. 270-289, (2019) (PubMed).

Won, Moreira, Gao, Duttagupta, Zhao, Manuel, Diamond, Yuan, Liu, Jones, DApuzzo, Pal, Kortylewski: "TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs." in: Journal of leukocyte biology, Vol. 102, Issue 2, pp. 423-436, (2017) (PubMed).

Hammoud, Kirstein, Mournetas, Darracq, Broc, Blanchard, Zeineddine, Mortada, Boeuf: "Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146281, (2016) (PubMed).

Murphy, Halow, Royer, Hennebold: "Leukemia Inhibitory Factor Is Necessary for Ovulation in Female Rhesus Macaques." in: Endocrinology, Vol. 157, Issue 11, pp. 4378-4387, (2016) (PubMed).

Reinartz, Finkernagel, Adhikary, Rohnalter, Schumann, Schober, Nockher, Nist, Stiewe, Jansen, Wagner, Müller-Brüsselbach, Müller: "A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome." in: Genome biology, Vol. 17, Issue 1, pp. 108, (2016) (PubMed).

McIntyre, Alev, Mechael, Salci, Lee, Fiebig-Comyn, Guezguez, Wu, Sheng, Bhatia: "Expansive generation of functional airway epithelium from human embryonic stem cells." in: Stem cells translational medicine, Vol. 3, Issue 1, pp. 7-17, (2014) (PubMed).

Larsen, Hansen, Møller, Madsen, Scheller, Nielsen, Petersen: "Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer." in: Molecular and cellular biology, Vol. 30, Issue 17, pp. 4175-87, (2010) (PubMed).

Erices, Conget, Rojas, Minguell: "Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells." in: Experimental cell research, Vol. 280, Issue 1, pp. 24-32, (2002) (PubMed).

Synonyme und alternative Namen zu LIFR

leukemia inhibitory factor receptor (Lifr), LIF receptor alpha (LOC397451), LIF receptor alpha (LIFR), LIF receptor alpha (Lifr), leukemia inhibitory factor receptor alpha (LIFR), A230075M04Rik, AW061234, CD118, LIF, LIF-R, SJS2, STWS, SWS

Bezeichner auf Proteinebene für LIFR

  • D-factor/LIF receptor
  • LIF receptor
  • LIF-R
  • leukemia inhibitory factor receptor alpha chain
  • soluble differentiation-stimulating factor receptor
  • CD118 antigen
  • leukemia inhibitory factor receptor
  • leukemia inhibitor factor receptor alpha-chain
  • cytokine receptor-beta
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