LILRB4 Produkte
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
Kategorien
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
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Ausgewählte LILRB4 Kategorien
LILRB4 Antikörper
High quality antibodies with extensive validation data.
LILRB4 ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene LILRB4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN6143221
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7440272
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7158277
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LILRB4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968284
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975432
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957469
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LILRB4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (5)
Kat. Nr.
ABIN7275170
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275191
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275159
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LILRB4 Produkten
: "Interferon beta and vitamin D synergize to induce immunoregulatory receptors on peripheral blood monocytes of multiple sclerosis patients." in: PLoS ONE, Vol. 9, Issue 12, pp. e115488, (2015) (PubMed).: "Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo. ..." in: Nature immunology, Vol. 16, Issue 3, pp. 267-75, (2015) (PubMed).
: "Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 5, pp. 2110-7, (2012) (PubMed).
: "Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e22504, (2011) (PubMed).
: "DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function." in: Journal of leukocyte biology, Vol. 89, Issue 6, pp. 893-905, (2011) (PubMed).
: "Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 3966-76, (2011) (PubMed).
: "Cytokine induced expression of programmed death ligands in human neutrophils." in: Immunology letters, Vol. 129, Issue 2, pp. 100-7, (2010) (PubMed).
: "Phenotypic and functional markers for 1alpha,25-dihydroxyvitamin D(3)-modified regulatory dendritic cells." in: Clinical and experimental immunology, Vol. 157, Issue 1, pp. 48-59, (2009) (PubMed).
: "Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X." in: Journal of leukocyte biology, Vol. 84, Issue 5, pp. 1306-15, (2008) (PubMed).
: "Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals." in: The Journal of experimental medicine, Vol. 205, Issue 8, pp. 1797-805, (2008) (PubMed).
Synonyme und alternative Namen zu LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4), leukocyte immunoglobulin like receptor B4 (LILRB4), leukocyte immunoglobulin-like receptor, subfamily B, member 4A (Lilrb4a), CD85K, gp49, Gp49b, HM18, ILT-3, ILT3, LIR-5, LIR5Bezeichner auf Proteinebene für LILRB4
- leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
- CD85 antigen-like family member K
- immunoglobulin-like transcript 3
- leukocyte immunoglobulin-like receptor 5
- leukocyte immunoglobulin-like receptor subfamily B member 4
- monocyte inhibitory receptor HM18
- glycoprotein 49 B
- mast cell surface glycoprotein Gp49B
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