LIM Domain Binding 3 Produkte
(LIM Domain Binding 3 (LDB3))
Kategorien
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified\; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010].
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Ausgewählte LIM Domain Binding 3 Kategorien
LIM Domain Binding 3 Antikörper
High quality antibodies with extensive validation data.
LIM Domain Binding 3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LIM Domain Binding 3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, RNAi
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN524582
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IF
Validierungen
- (5)
Kat. Nr.
ABIN7263475
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN6143125
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LIM Domain Binding 3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6205510
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LIM Domain Binding 3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309259
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3082876
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3130255
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LIM Domain Binding 3 Produkten
: "Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13615-26, (2014) (PubMed).: "Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole." in: Circulation, Vol. 129, Issue 19, pp. 1924-36, (2014) (PubMed).
: "Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked β-N-acetylglucosamine-substituted protein in human heart myofibrils." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4891-8, (2013) (PubMed).
: "Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy." in: Cardiovascular research, Vol. 83, Issue 1, pp. 80-8, (2009) (PubMed).
: "Mutations in ZASP define a novel form of muscular dystrophy in humans." in: Annals of neurology, Vol. 57, Issue 2, pp. 269-76, (2005) (PubMed).
: "Characterization and in vivo functional analysis of splice variants of cypher." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7360-5, (2003) (PubMed).
Synonyme und alternative Namen zu LIM Domain Binding 3
LIM domain binding 3 (LDB3), LIM domain binding 3 (Ldb3), LIM domain binding 3b (ldb3b), LIM domain binding 3 S homeolog (ldb3.S), LIM domain binding 3 (ldb3), LIM domain binding 3a (ldb3a), AW742271, CMD1C, CYPHER, cypher, hm:zehn1639, ldb3, LDB3, ldb3l, LDB3Z1, LDB3Z4, LVNC3, MFM4, MGC52706, MGC75668, ORACLE, PDLIM6, RGD1564875, wu:fi31d08, ZASP, zehn1639, zgc:55814Bezeichner auf Proteinebene für LIM Domain Binding 3
- LIM domain-binding protein 3
- PDZ and LIM domain 6
- Z-band alternatively spliced PDZ-motif protein
- protein cypher
- PDZ-LIM domain protein
- cypher
- oracle protein
- protein oracle
- LIM domain binding 3
- LIM domain binding 3 like
- LIM-domain binding factor 3, like
- LIM-domain binding factor 3a
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