LITAF Produkte
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Kategorien
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008].
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Ausgewählte LITAF Kategorien
LITAF Antikörper
High quality antibodies with extensive validation data.
LITAF ELISA Kits
Reliable ELISA kits for a wide range of species.
LITAF Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LITAF Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN523000
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7158438
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7074508
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LITAF ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Chicken
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5593872
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1140821
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1140824
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LITAF Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123779
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN1098763
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309476
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LITAF Produkten
: "Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes." in: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1619-37, S1-3, (2013) (PubMed).: "LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 37, pp. 13777-82, (2006) (PubMed).
: "SIMPLE mutations in Charcot-Marie-Tooth disease and the potential role of its protein product in protein degradation." in: Human mutation, Vol. 25, Issue 4, pp. 372-83, (2005) (PubMed).
: "Mycobacterium bovis Bacillus Calmette-Guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible gene, LITAF(PIG7), and estrogen-inducible gene, EET-1." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 23065-76, (2001) (PubMed).
: "A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor alpha gene expression: molecular cloning, sequencing, characterization, and chromosomal assignment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4518-23, (1999) (PubMed).
Synonyme und alternative Namen zu LITAF
lipopolysaccharide induced TNF factor (LITAF), lipopolysaccharide-induced TNF factor (Litaf), LPS-induced TN factor (Litaf), 3222402J11Rik, C85531, EET-1, N4WBP3, PIG7, Pig7, SIMPLE, TBX1, TNF-alpha, TP53I7Bezeichner auf Proteinebene für LITAF
- LPS-induced TNF-alpha factor
- lipopolysaccharide-induced TNF-alpha factor
- lipopolysaccharide-induced tumor necrosis factor-alpha factor
- p53-induced gene 7 protein
- small integral membrane protein of lysosome/late endosome
- tumor protein p53 inducible protein 7
- LPS-induced TN factor
- LPS-induced TNF-alpha factor homolog
- estrogen-enhanced transcript protein 1
- estrogen-responsive uterine transcript
- lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
- TNF-alpha factor
- lipid-induced TNF-alpha factor
- tissue necrosis factor-alpha
- LITAF-like protein
- Nedd4 WW domain-binding protein 3
- estrogen-enhanced transcript protein
- mEET
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