LONP1 Produkte
(Lon Peptidase 1, Mitochondrial (LONP1))
Kategorien
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013].
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Ausgewählte LONP1 Kategorien
LONP1 Antikörper
High quality antibodies with extensive validation data.
LONP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LONP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (5)
Kat. Nr.
ABIN705806
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN522820
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (4)
Kat. Nr.
ABIN1680707
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene LONP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6227622
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LONP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309661
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309659
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LONP1 Produkten
: "Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells." in: PLoS ONE, Vol. 14, Issue 3, pp. e0213283, (2019) (PubMed).: "Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1." in: Molecular cell, Vol. 73, Issue 5, pp. 1028-1043.e5, (2019) (PubMed).
: "Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration." in: Cell death & disease, Vol. 9, Issue 3, pp. 304, (2018) (PubMed).
: "Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis." in: Scientific reports, Vol. 8, Issue 1, pp. 1163, (2018) (PubMed).
: "Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation." in: Cell death discovery, Vol. 4, pp. 51, (2018) (PubMed).
: "ATP-Dependent Lon Protease Contributes to Helicobacter pylori-Induced Gastric Carcinogenesis." in: Neoplasia (New York, N.Y.), Vol. 18, Issue 4, pp. 242-52, (2016) (PubMed).
: "Proteomic analysis of mitochondrial-associated ER membranes (MAM) during RNA virus infection reveals dynamic changes in protein and organelle trafficking." in: PLoS ONE, Vol. 10, Issue 3, pp. e0117963, (2015) (PubMed).
: "PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix." in: PLoS genetics, Vol. 10, Issue 5, pp. e1004279, (2014) (PubMed).
: "The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria." in: Autophagy, Vol. 9, Issue 11, pp. 1750-7, (2013) (PubMed).
: "Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman." in: Case reports in gastroenterology, Vol. 2, Issue 3, pp. 474-8, (2011) (PubMed).
Synonyme und alternative Namen zu LONP1
lon peptidase 1, mitochondrial (LONP1), lon peptidase 1, mitochondrial (lonp1), lon peptidase 1, mitochondrial (Lonp1), ATP-dependent Lon protease (PIM1), 1200017E13Rik, fc64d11, hLON, LON, Lon, LonHS, LONP, PIM1, PRSS15, prss15, Prss15, wu:fc64d11Bezeichner auf Proteinebene für LONP1
- lon peptidase 1, mitochondrial
- protease, serine, 15
- lon protease homolog, mitochondrial-like
- hLON ATP-dependent protease
- lon protease homolog, mitochondrial
- mitochondrial ATP-dependent protease Lon
- mitochondrial lon protease-like protein
- serine protease 15
- LONP
- lon protease-like protein
- ATP-dependent Lon protease
- hypothetical protein
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