CD34 molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. The CD34 protein is a member of a family of single- pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular- associated tissue. However little is known about its exact function. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L- selectin to which it binds is on the T cell. Conversely, under other circumstances CD34 has been shown to act as molecular \\
Lysed Cells
HEK 293T Cells
Lysate Type
Overexpression Lysate
Lysate Fraction
Whole Cell Lysate
Applikationshinweise
CD34 (h): 293T Lysate is suitable as a Western Blotting positive control for human reactive CD34 antibodies. Recommended use: 10-20 µl per lane. Control 293T Lysate: 293LYS is available as a Western Blotting negative control lysate derived from non-transfected 293T cells.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
Repeated freezing and thawing should be minimized. Sample vial should be boiled once prior to use. Non-hazardous. No MSDS required.
Lagerung
-20 °C
Park, Tait, Kawasaki, Rowley, Mackay: "Closer association of IA-2 humoral autoreactivity with HLA DR3/4 than DQB1*0201/*0302 in Korean T1D patients." in: Annals of the New York Academy of Sciences, Vol. 1037, pp. 104-9, (2005) (PubMed).
Iwama, Ikezaki, Kikuoka, Kim, Matsuoka, Yanagawa, Sato, Hoshi, Sakamaki, Sugihara: "Association of HLA-DR, -DQ genotype and CTLA-4 gene polymorphism with Graves' disease in Japanese children." in: Hormone research, Vol. 63, Issue 2, pp. 55-60, (2005) (PubMed).
Spriewald, Witzke, Wassmuth, Wenzel, Arnold, Philipp, Kalden: "Distinct tumour necrosis factor alpha, interferon gamma, interleukin 10, and cytotoxic T cell antigen 4 gene polymorphisms in disease occurrence and end stage renal disease in Wegener's granulomatosis." in: Annals of the rheumatic diseases, Vol. 64, Issue 3, pp. 457-61, (2005) (PubMed).
Voorter, de Groot, Meertens, Bontrop, van den Berg-Loonen: "Allelic polymorphism in introns 1 and 2 of the HLA-DQA1 gene." in: Tissue antigens, Vol. 65, Issue 1, pp. 56-66, (2005) (PubMed).
Arnold, Pei, Spriewald, Wassmuth: "Anti-HLA class II antibodies in kidney retransplant patients." in: Tissue antigens, Vol. 65, Issue 4, pp. 370-8, (2005) (PubMed).
Quintero, Pizarro, Rodrigo, Piqué, Lanas, Ponce, Miño, Gisbert, Jurado, Herrero, Jiménez, Torrado, Ponte, Díaz-de-Rojas, Salido: "Association of Helicobacter pylori-related distal gastric cancer with the HLA class II gene DQB10602 and cagA strains in a southern European population." in: Helicobacter, Vol. 10, Issue 1, pp. 12-21, (2005) (PubMed).