Macrophage Scavenger Receptor 1 Produkte
(Macrophage Scavenger Receptor 1 (MSR1))
Kategorien
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008].
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Ausgewählte Macrophage Scavenger Receptor 1 Kategorien
Macrophage Scavenger Receptor 1 Antikörper
High quality antibodies with extensive validation data.
Macrophage Scavenger Receptor 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Macrophage Scavenger Receptor 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Macrophage Scavenger Receptor 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Sheep
Applikation
WB, ELISA, FACS, IHC (fro), IF (p), IF (cc), IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN872905
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (5)
Kat. Nr.
ABIN7193254
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6263400
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Macrophage Scavenger Receptor 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957614
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968418
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6973534
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Macrophage Scavenger Receptor 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275296
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN5854557
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311469
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Macrophage Scavenger Receptor 1 Produkten
: "Mechanism of TGF-β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis." in: Experimental and therapeutic medicine, Vol. 20, Issue 2, pp. 1541-1549, (2020) (PubMed).: "Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development." in: Cell reports, Vol. 31, Issue 12, pp. 107802, (2020) (PubMed).
: "Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study." in: Nature communications, Vol. 11, Issue 1, pp. 1911, (2020) (PubMed).
: "Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis." in: Arthritis research & therapy, Vol. 20, Issue 1, pp. 46, (2018) (PubMed).
: "Effect of Orally Administered Atractylodes macrocephala Koidz Water Extract on Macrophage and T Cell Inflammatory Response in Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 4041873, (2018) (PubMed).
: "Bushfire smoke is pro-inflammatory and suppresses macrophage phagocytic function." in: Scientific reports, Vol. 8, Issue 1, pp. 13424, (2018) (PubMed).
: "Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation." in: International immunology, Vol. 29, Issue 2, pp. 59-70, (2017) (PubMed).
: "Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1516-1525, (2017) (PubMed).
: "Phagocytosis and Inflammation: Exploring the effects of the components of E-cigarette vapor on macrophages." in: Physiological reports, Vol. 5, Issue 16, (2017) (PubMed).
: "Combination of plasma HA and circulating M2-like monocytes may serve as a diagnostic marker for breast cancer." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3522-3530, (2017) (PubMed).
Synonyme und alternative Namen zu Macrophage Scavenger Receptor 1
macrophage scavenger receptor 1 (MSR1), macrophage scavenger receptor 1 (Msr1), scavenger receptor class A member 5 (SCARA5), CD204, MRS-A, MSR, MSR-A, MSR1, phSR1, phSR2, RGD1564316, SCARA1, Scara1, Scvr, SR-A, SR-AI, SR-AII, SRABezeichner auf Proteinebene für Macrophage Scavenger Receptor 1
- macrophage acetylated LDL receptor I and II
- macrophage scavenger receptor type III
- macrophage scavenger receptor types I and II
- scavenger receptor class A member 1
- scavenger receptor class A, member 1
- SR-A
- scavenger receptor type A
- macrophage scavenger receptor 1
- macrophage scavenger receptor type I
- macrophage scavenger receptor types I and II-like
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