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MADD Produkte

(MAP-Kinase Activating Death Domain (MADD))

Kategorien

Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte MADD Kategorien

MADD Antikörper

High quality antibodies with extensive validation data.

MADD ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene MADD Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7187234
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN3185435
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN1534033
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MADD ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648202
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MADD Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7422859
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7421455
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MADD Produkten

Yoshimura, Gerondopoulos, Linford, Rigden, Barr: "Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors." in: The Journal of cell biology, Vol. 191, Issue 2, pp. 367-81, (2010) (PubMed).

Jing, Yu, Fang, Hu, Holst, Boone, Delaney, Schultz, Zhou, Fox: "GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family." in: The Journal of biological chemistry, Vol. 272, Issue 52, pp. 33111-7, (1998) (PubMed).

Milbrandt, de Sauvage, Fahrner, Baloh, Leitner, Tansey, Lampe, Heuckeroth, Kotzbauer, Simburger, Golden, Davies, Vejsada, Kato, Hynes, Sherman, Nishimura, Wang, Vandlen, Moffat, Klein, Poulsen, Gray et al.: "Persephin, a novel neurotrophic factor related to GDNF and neurturin. ..." in: Neuron, Vol. 20, Issue 2, pp. 245-53, (1998) (PubMed).

Baloh, Gorodinsky, Golden, Tansey, Keck, Popescu, Johnson, Milbrandt: "GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 10, pp. 5801-6, (1998) (PubMed).

Synonyme und alternative Namen zu MADD

MAP kinase activating death domain (MADD), MAP-kinase activating death domain (madd), MAP kinase activating death domain (madd), MAP-kinase activating death domain (Madd), 9630059K23Rik, DENN, IG20, MADD, MGC145371, RAB3GEP

Bezeichner auf Proteinebene für MADD

  • MAP-kinase activating death domain
  • MAP kinase-activating death domain protein
  • MAP kinase-activating death domain protein-like
  • Rab3 GDP/GTP exchange factor
  • differentially expressed in normal and neoplastic cells
  • insulinoma glucagonoma clone 20
  • Rab3 GDP/GTP exchange protein
  • Rab3 GEP
  • insulinoma-glucagonoma protein 20
  • rab3 GDP/GTP exchange factor
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