MADD Produkte
(MAP-Kinase Activating Death Domain (MADD))
Kategorien
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte MADD Kategorien
MADD Antikörper
High quality antibodies with extensive validation data.
MADD ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene MADD Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7187234
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN3185435
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (fro)
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2475471
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene MADD ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648202
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MADD Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422859
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7421455
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MADD Produkten
: "Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors." in: The Journal of cell biology, Vol. 191, Issue 2, pp. 367-81, (2010) (PubMed).: "GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family." in: The Journal of biological chemistry, Vol. 272, Issue 52, pp. 33111-7, (1998) (PubMed).
: "Persephin, a novel neurotrophic factor related to GDNF and neurturin. ..." in: Neuron, Vol. 20, Issue 2, pp. 245-53, (1998) (PubMed).
: "GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 10, pp. 5801-6, (1998) (PubMed).
Synonyme und alternative Namen zu MADD
MAP kinase activating death domain (MADD), MAP-kinase activating death domain (madd), MAP kinase activating death domain (madd), MAP-kinase activating death domain (Madd), 9630059K23Rik, DENN, IG20, MADD, MGC145371, RAB3GEPBezeichner auf Proteinebene für MADD
- MAP-kinase activating death domain
- MAP kinase-activating death domain protein
- MAP kinase-activating death domain protein-like
- Rab3 GDP/GTP exchange factor
- differentially expressed in normal and neoplastic cells
- insulinoma glucagonoma clone 20
- Rab3 GDP/GTP exchange protein
- Rab3 GEP
- insulinoma-glucagonoma protein 20
- rab3 GDP/GTP exchange factor
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