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MAP3K7 Produkte

(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Kategorien

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Ausgewählte MAP3K7 Kategorien

MAP3K7 Antikörper

High quality antibodies with extensive validation data.

MAP3K7 ELISA Kits

Reliable ELISA kits for a wide range of species.

MAP3K7 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MAP3K7 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (10)
Kat. Nr. ABIN6256492
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN6143503
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IP
Validierungen
  • (5)
Kat. Nr. ABIN948522
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MAP3K7 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957869
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380474
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380773
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene MAP3K7 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1310225
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310227
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3093681
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MAP3K7 Produkten

Huang, Chiang, Hung, Hou: "Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer." in: Oncotarget, Vol. 6, Issue 2, pp. 995-1007, (2015) (PubMed).

Salazar, Kashiwada, Krejci, Meyer, Casale, Hallowell, Wilcox, Donoghue, Thompson: "Fibroblast growth factor receptor 3 interacts with and activates TGF?-activated kinase 1 tyrosine phosphorylation and NF?B signaling in multiple myeloma and bladder cancer." in: PLoS ONE, Vol. 9, Issue 1, pp. e86470, (2014) (PubMed).

Lei, Han, Xiao, Jin, He, Wang: "Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex." in: Journal of virology, Vol. 88, Issue 17, pp. 9830-41, (2014) (PubMed).

Sorrentino, Thakur, Grimsby, Marcusson, von Bulow, Schuster, Zhang, Heldin, Landström: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." in: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).

Liu, Yao, Li, Wang, Zheng, Cao: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." in: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).

Ahn, Rong, Kroll, Van Meir, Snyder, Ye: "PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16441-51, (2004) (PubMed).

Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: "Wnt activates the Tak1/Nemo-like kinase pathway." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17232-40, (2004) (PubMed).

Akira, Takeda: "Toll-like receptor signalling." in: Nature reviews. Immunology, Vol. 4, Issue 7, pp. 499-511, (2004) (PubMed).

Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: "A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta." in: Biochemical and biophysical research communications, Vol. 307, Issue 2, pp. 332-7, (2003) (PubMed).

Sakurai, Suzuki, Kawasaki, Nakano, Okazaki, Chino, Doi, Saiki: "Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36916-23, (2003) (PubMed).

Synonyme und alternative Namen zu MAP3K7

mitogen-activated protein kinase kinase kinase 7 (map3k7), mitogen activated protein kinase kinase kinase 7 (Map3k7), mitogen-activated protein kinase kinase kinase 7 (MAP3K7), mitogen-activated protein kinase kinase kinase 7 (Map3k7), B430101B05, C87327, MEKK7, si:ch211-225h9.1, Tak1, TAK1, TGF1a, zgc:110612

Bezeichner auf Proteinebene für MAP3K7

  • mitogen-activated protein kinase kinase kinase 7
  • tak1
  • TGF-beta-activated kinase TAK1
  • TGF-beta activated kinase 1
  • TGF-beta-activated kinase 1
  • transforming growth factor-beta-activated kinase 1
  • mitogen activated protein kinase kinase kinase 7
  • transforming growth factor beta-activated kinase 1
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