MAP3K9 Produkte
(Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))
Kategorien
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
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Ausgewählte MAP3K9 Kategorien
MAP3K9 Antikörper
High quality antibodies with extensive validation data.
MAP3K9 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MAP3K9 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (4)
Kat. Nr.
ABIN872294
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7160061
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN392422
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene MAP3K9 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310241
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509016
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3093690
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MAP3K9 Produkten
: "Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure." in: Hearing research, Vol. 270, Issue 1-2, pp. 21-7, (2011) (PubMed).: "Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22426-36, (2010) (PubMed).
: "Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation." in: BMC genomics, Vol. 10, pp. 67, (2009) (PubMed).
: "Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop." in: Biochemistry, Vol. 43, Issue 51, pp. 16348-55, (2004) (PubMed).
: "Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex." in: The Journal of biological chemistry, Vol. 278, Issue 48, pp. 47922-7, (2003) (PubMed).
: "The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4713-24, (2001) (PubMed).
Synonyme und alternative Namen zu MAP3K9
mitogen-activated protein kinase kinase kinase 9 (MAP3K9), mitogen-activated protein kinase kinase kinase 9 (Map3k9), E130314H24Rik, MEKK9, MLK1, Mlk1, PRKE1, Prke1, RGD1562149Bezeichner auf Proteinebene für MAP3K9
- mixed lineage kinase 1 (tyr and ser/thr specificity)
- mitogen activated protein kinase kinase kinase 9
- mixed-lineage kinase 1
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