MAPK8IP1 Produkte
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Kategorien
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011].
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Ausgewählte MAPK8IP1 Kategorien
MAPK8IP1 Antikörper
High quality antibodies with extensive validation data.
MAPK8IP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MAPK8IP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (4)
Kat. Nr.
ABIN652961
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN2854806
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF, IHC
Validierungen
- (2)
Kat. Nr.
ABIN3185263
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MAPK8IP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6227128
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MAPK8IP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3093174
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3137545
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2725443
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MAPK8IP1 Produkten
: "Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons." in: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 35113-8, (2000) (PubMed).: "IB1, a JIP-1-related nuclear protein present in insulin-secreting cells." in: The Journal of biological chemistry, Vol. 273, Issue 4, pp. 1843-6, (1998) (PubMed).
: "A cytoplasmic inhibitor of the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 277, Issue 5326, pp. 693-6, (1997) (PubMed).
Synonyme und alternative Namen zu MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1), mitogen-activated protein kinase 8 interacting protein 1 (Mapk8ip1), IB1, JIP-1, Jip-1, Jip1, JIP1, Mapk8ip, mjip-2a, Prkm8ip, PRKM8IP, SkipBezeichner auf Proteinebene für MAPK8IP1
- mitogen-activated protein kinase 8 interacting protein 1
- c-Jun-amino-terminal kinase-interacting protein 1-like
- C-Jun-amino-terminal kinase-interacting protein 1
- IB-1
- JNK MAP kinase scaffold protein 1
- JNK-interacting protein 1
- islet-brain-1
- mitogen activated protein kinase 8 interacting protein 1
- mitogen-activated protein kinase 8-interacting protein 1
- protein kinase, mitogen-activated 8 interacting protein
- JIP-1-related protein
- JRP
- mitogen activated protein kinase 8 interacting protein
- PRKM8 interacting protein
- islet-brain 1
- islet brain 1
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