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MATK Produkte

(Megakaryocyte-Associated tyrosine Kinase (MATK))
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte MATK Kategorien

MATK Antikörper

High quality antibodies with extensive validation data.

MATK ELISA Kits

Reliable ELISA kits for a wide range of species.

MATK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MATK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN7159178
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN969495
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, ICC, IF
Validierungen
  • (3)
Kat. Nr. ABIN6259101
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MATK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4886198
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Various Species
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN5594938
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1141899
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MATK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310443
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310445
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509002
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MATK Produkten

McShan, Zagozdzon, Park, Zrihan-Licht, Fu, Avraham, Avraham: "Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." in: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).

Zagozdzon, Bougeret, Fu, Avraham: "Overexpression of the Csk homologous kinase facilitates phosphorylation of Akt/PKB in MCF-7 cells." in: International journal of oncology, Vol. 21, Issue 6, pp. 1347-52, (2002) (PubMed).

Kim, Zagozdzon, Meisler, Baleja, Fu, Avraham, Avraham: "Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36465-70, (2002) (PubMed).

Synonyme und alternative Namen zu MATK

megakaryocyte-associated tyrosine kinase (matk), megakaryocyte-associated tyrosine kinase (MATK), megakaryocyte-associated tyrosine kinase (Matk), zinc finger RNA binding protein 2 (ZFR2), Batk, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk, Ntk, si:ch211-63j24.2

Bezeichner auf Proteinebene für MATK

  • megakaryocyte-associated tyrosine kinase
  • megakaryocyte-associated tyrosine-protein kinase-like
  • CSK homologous kinase
  • Csk-homologous kinase
  • Csk-type protein tyrosine kinase
  • HYL tyrosine kinase
  • hematopoietic consensus tyrosine-lacking kinase
  • hydroxyaryl-protein kinase
  • leukocyte carboxyl-terminal src kinase related
  • megakaryocyte-associated tyrosine-protein kinase
  • protein kinase HYL
  • tyrosine kinase MATK
  • tyrosine-protein kinase CTK
  • tyrosylprotein kinase
  • Csk homologous kinase
  • protein kinase NTK
  • megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase)
  • non-receptor protein kinase protein
  • protein kinase BATK
  • carboxyl-terminal SRC kinase homologous kinase
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