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MAX Produkte

(MYC Associated Factor X (MAX))

Kategorien

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Ausgewählte MAX Kategorien

MAX Antikörper

High quality antibodies with extensive validation data.

MAX ELISA Kits

Reliable ELISA kits for a wide range of species.

MAX Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MAX Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, PLA
Validierungen
  • (4)
Kat. Nr. ABIN561745
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN184586
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7165797
Menge 100 μg
Datenblatt Datenblatt

Empfohlene MAX ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968708
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957925
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951174
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MAX Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN666983
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310452
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN1097137
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MAX Produkten

Wang, Yang, Zhang, Guo, Wu, Wang, Jia, Li, Xie, Yang: "lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer." in: Cancer cell, Vol. 33, Issue 4, pp. 706-720.e9, (2019) (PubMed).

Pichulik, Khatamzas, Liu, Brain, Delmiro Garcia, Leslie, Danis, Mayer, Baban, Ragoussis, Weber, Simmons: "Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus." in: European journal of immunology, Vol. 46, Issue 1, pp. 167-77, (2016) (PubMed).

Ikeda, Pak, Chavez, Ryan: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).

Qin, de Cubas, Garcia-Martin, Richter, Peitzsch, Menschikowski, Lenders, Timmers, Mannelli, Opocher, Economopoulou, Siegert, Chavakis, Pacak, Robledo, Eisenhofer: "Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X." in: International journal of cancer, Vol. 135, Issue 9, pp. 2054-64, (2014) (PubMed).

Faiola, Wu, Pan, Zhang, Farina, Martinez: "Max is acetylated by p300 at several nuclear localization residues." in: The Biochemical journal, Vol. 403, Issue 3, pp. 397-407, (2007) (PubMed).

Gordan, Bertout, Hu, Diehl, Simon: "HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity." in: Cancer cell, Vol. 11, Issue 4, pp. 335-47, (2007) (PubMed).

Fujii, Lyakh, Bracken, Fukuoka, Hayakawa, Tsukiyama, Soll, Harris, Rocha, Roche, Tominaga, Jen, Perkins, Lechleider, Roberts: "SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes." in: Molecular cell, Vol. 24, Issue 5, pp. 771-83, (2006) (PubMed).

Magid, Murphy, Galis: "Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32994-9, (2003) (PubMed).

Blackwood, Eisenman: "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc." in: Science (New York, N.Y.), Vol. 251, Issue 4998, pp. 1211-7, (1991) (PubMed).

Synonyme und alternative Namen zu MAX

CG9648 gene product from transcript CG9648-RD (Max), MYC associated factor X L homeolog (max.L), MYC associated factor X (MAX), MYC associated factor X (max), Max protein (Max), MYC associated factor X S homeolog (max.S), MYC associated factor X (Max), myc associated factor X (max), AA960152, AI875693, bhlhd4, bHLHd4, bhlhd5, bHLHd5, bhlhd6, bHLHd6, bhlhd7, bHLHd7, bhlhd8, bHLHd8, bHLHd9, CG9648, dMax, dmax, Dmel\\CG9648, fa92b04, fb52a04, fb95h11, MAX, max, wu:fa92b04, wu:fb52a04, wu:fb95h11, xmax, xmax2, xmax4, zmax

Bezeichner auf Proteinebene für MAX

  • CG9648-PA
  • CG9648-PC
  • Max-PA
  • Max-PC
  • Max homologue 2
  • Myc binding protein Xmax4
  • myc-associated factor X
  • protein max
  • xMAX
  • MYC associated factor X
  • myc-binding novel HLH/LZ protein
  • protein myn
  • class D basic helix-loop-helix protein 4
  • Myc binding protein Xmax2
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