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MBD1 Produkte

(Methyl-CpG Binding Domain Protein 1 (MBD1))

Kategorien

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011].

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Ausgewählte MBD1 Kategorien

MBD1 Antikörper

High quality antibodies with extensive validation data.

MBD1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MBD1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MBD1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN517760
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN517761
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN517757
Menge 50 μL
Datenblatt Datenblatt

Empfohlene MBD1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1142345
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1142346
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MBD1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1310462
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310463
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7423543
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MBD1 Produkten

Hendriks, Treffers, Verlaan-de Vries, Olsen, Vertegaal: "SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage." in: Cell reports, (2015) (PubMed).

Varshney, Vavrova-Anderson, Oler, Cowling, Cairns, White: "SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation." in: Nature communications, Vol. 6, pp. 6569, (2015) (PubMed).

Staples, Myers, Beveridge, Patil, Howard, Barone, Lee, Swanton, Howell, Maslen, Skehel, Boulton, Collis: "Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability." in: Journal of cell science, Vol. 127, Issue Pt 13, pp. 2910-9, (2014) (PubMed).

Waterfield, Khan, Cortez, Fan, Metzger, Greer, Fasano, Martinez-Llordella, Pollack, Erle, Su, Anderson: "The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance." in: Nature immunology, Vol. 15, Issue 3, pp. 258-65, (2014) (PubMed).

Staples, Myers, Beveridge, Patil, Lee, Swanton, Howell, Boulton, Collis: "The centriolar satellite protein Cep131 is important for genome stability." in: Journal of cell science, Vol. 125, Issue Pt 20, pp. 4770-9, (2012) (PubMed).

Jin, Kadam, Pfeifer: "Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine." in: Nucleic acids research, Vol. 38, Issue 11, pp. e125, (2010) (PubMed).

Zhao, Wu, Bu, Lu, Liang, Cao, Tong, Lu, Wu, Guo et al.: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).

Kumar, Verma: "Methods in cancer epigenetics and epidemiology." in: Methods in molecular biology (Clifton, N.J.), Vol. 471, pp. 273-88, (2008) (PubMed).

Ruddock-DCruz, Xue, Wilson, Heffernan, Prashadkumar, Cooney, Sanchez-Partida, French, Holland: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." in: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).

Villa, Pasini, Gutierrez, Morey, Occhionorelli, Viré, Nomdedeu, Jenuwein, Pelicci, Minucci, Fuks, Helin, Di Croce: "Role of the polycomb repressive complex 2 in acute promyelocytic leukemia." in: Cancer cell, Vol. 11, Issue 6, pp. 513-25, (2007) (PubMed).

Synonyme und alternative Namen zu MBD1

methyl-CpG binding domain protein 1 (MBD1), methyl-CpG binding domain protein 1 (Mbd1), CCDC11, CXXC3, Cxxc3, PCM1, RFT

Bezeichner auf Proteinebene für MBD1

  • CXXC-type zinc finger protein 3
  • methyl-CpG binding domain protein 1 isoform PCM1
  • methyl-CpG-binding domain protein 1
  • protein containing methyl-CpG-binding domain 1
  • the regulator of fibroblast growth factor 2 (FGF-2) transcription
  • methyl-CpG-binding protein MBD1
  • coiled-coil domain containing 11
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