MBD4 Produkte
(Methyl-CpG Binding Domain Protein 4 (MBD4))
Kategorien
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013].
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Ausgewählte MBD4 Kategorien
MBD4 Antikörper
High quality antibodies with extensive validation data.
MBD4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MBD4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1881532
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN3044062
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Guinea Pig, Human
Applikation
WB, ChIP
Validierungen
- (2)
Kat. Nr.
ABIN2776028
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MBD4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6224403
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MBD4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123938
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310474
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310473
Menge
25 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MBD4 Produkten
: "Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis." in: British journal of cancer, Vol. 110, Issue 3, pp. 668-78, (2014) (PubMed).: "Polymorphisms in the base excision repair pathway and graft-versus-host disease." in: Leukemia, Vol. 24, Issue 8, pp. 1470-5, (2010) (PubMed).
: "Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations." in: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, Vol. 16, Issue 8, pp. 1084-9, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." in: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).
: "Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples." in: Human molecular genetics, Vol. 14, Issue 6, pp. 785-97, (2005) (PubMed).
Synonyme und alternative Namen zu MBD4
methyl-CpG binding domain 4, DNA glycosylase (MBD4), methyl-CpG binding domain protein 4 (Mbd4), methyl-CpG binding domain 4 DNA glycosylase (Mbd4), MED1, Med1Bezeichner auf Proteinebene für MBD4
- 3,N(4)-ethenocytosine glycosylase
- G/5-fluorouracil mismatch glycosylase with biphasic kinetics
- G/T mismatch glycosylase
- G/U mismatch glycosylase
- methyl-CpG-binding domain protein 4
- methyl-CpG-binding endonuclease 1
- methyl-CpG-binding protein MBD4
- mismatch-specific DNA N-glycosylase
- putative methyl-CpG binding protein
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