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MCAM Produkte

(Melanoma Cell Adhesion Molecule (MCAM))

Kategorien

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

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Ausgewählte MCAM Kategorien

MCAM Antikörper

High quality antibodies with extensive validation data.

MCAM ELISA Kits

Reliable ELISA kits for a wide range of species.

MCAM Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MCAM Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS, IHC, WB, ELISA
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN1724844
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, WB, IF, ELISA
Validierungen
  • (7)
Kat. Nr. ABIN7147325
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, WB, IF
Validierungen
  • (7)
Kat. Nr. ABIN6143621
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MCAM ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6962587
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN6960653
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960654
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MCAM Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275297
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275301
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1310514
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MCAM Produkten

Sun, Ji, Ma, Zhu, Chen, Wang, Qian, Wu, Hu, Huang, Zhang: "Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis." in: Frontiers in immunology, Vol. 11, pp. 1598, (2020) (PubMed).

Tarantini, Valcarcel-Ares, Toth, Yabluchanskiy, Tucsek, Kiss, Hertelendy, Kinter, Ballabh, Süle, Farkas, Baur, Sinclair, Csiszar, Ungvari: "Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice." in: Redox biology, Vol. 24, pp. 101192, (2019) (PubMed).

Zhan, Liu, Wang: "The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).

England, Jiang, Hernandez, Sun, Valdovinos, Ehlerding, Engle, Yang, Huang, Cai: "ImmunoPET Imaging of CD146 in Murine Models of Intrapulmonary Metastasis of Non-Small Cell Lung Cancer." in: Molecular pharmaceutics, Vol. 14, Issue 10, pp. 3239-3247, (2018) (PubMed).

Gao, Zhang, Wang, Liu, He, Liu, Wang, Feng, Yang, Wang, Meng, Yan: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).

Wang, Wang, Wu, Qiu, Li, Chu, Huang, Xu, Gong, Li: "Sox10+adult stem cells contribute to biomaterial encapsulation and microvascularization." in: Scientific reports, Vol. 7, pp. 40295, (2017) (PubMed).

De Luca, Carpanese, Rapanotti, Viguria, Forgione, Rotili, Fulci, Iorio, Quintieri, Chimenti, Bianchi, Rosato, Caccuri: "The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis." in: Oncotarget, Vol. 8, Issue 9, pp. 15520-15538, (2017) (PubMed).

Luo, Duan, Qian, Feng, Wu, Wang, Feng, Yang, Qin, Yan: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." in: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).

Zhang, Chen, Liu, Zhou, Hu, Zhou, Han, Chen: "Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).

Nodomi, Umeda, Saida, Kinehara, Hamabata, Daifu, Kato, Hiramatsu, Watanabe, Kuwahara, Iehara, Adachi, Konishi, Nakahata, Hosoi, Heike: "CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor." in: Oncogene, Vol. 35, Issue 40, pp. 5317-5327, (2016) (PubMed).

Synonyme und alternative Namen zu MCAM

melanoma cell adhesion molecule (MCAM), melanoma cell adhesion molecule (Mcam), melanoma cell adhesion molecule b (mcamb), 1-gicerin, AV025631, CD146, cd146, CD149, gicerin, id:ibd3512, mcam, MCAM, MUC18, Muc18, s-endo, s-gicerin

Bezeichner auf Proteinebene für MCAM

  • Gicerin
  • S-endo 1 endothelial-associated antigen
  • cell surface glycoprotein MUC18
  • cell surface glycoprotein P1H12
  • melanoma adhesion molecule
  • melanoma-associated antigen A32
  • melanoma-associated antigen MUC18
  • gicerin
  • l-gicerin
  • l-gicerin protein
  • cell adhesion molecule
  • HEMCAM
  • melanoma cell adhesion molecule
  • cell surface glycoprotein MUC18-like
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