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MCC Produkte

(Mutated in Colorectal Cancers (MCC))

Kategorien

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte MCC Kategorien

MCC Antikörper

High quality antibodies with extensive validation data.

MCC Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MCC Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (4)
Kat. Nr. ABIN950122
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, RNAi
Validierungen
  • (4)
Kat. Nr. ABIN561756
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7148294
Menge 100 μg
Datenblatt Datenblatt

Empfohlene MCC Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310523
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310525
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3091956
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MCC Produkten

Cheng, Wang, Ye, Huang, Liu, Wu, Sun, Xie, Wang, Xia: "'Default' generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival." in: Immunology, Vol. 143, Issue 4, pp. 618-30, (2014) (PubMed).

Gollmer, Asperti-Boursin, Tanaka, Okkenhaug, Vanhaesebroeck, Peterson, Fukui, Donnadieu, Stein: "CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway." in: Blood, Vol. 114, Issue 3, pp. 580-8, (2009) (PubMed).

Huang, Chiang, Kok, Kuo, Kuo: "Loss of heterozygosity of APC and MCC genes in oral squamous cell carcinomas in Taiwan." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 26, Issue 7, pp. 322-6, (1997) (PubMed).

Matsumine, Senda, Baeg, Roy, Nakamura, Noda, Toyoshima, Akiyama: "MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase." in: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10341-6, (1996) (PubMed).

McKie, Filipe, Lemoine: "Abnormalities affecting the APC and MCC tumour suppressor gene loci on chromosome 5q occur frequently in gastric cancer but not in pancreatic cancer." in: International journal of cancer. Journal international du cancer, Vol. 55, Issue 4, pp. 598-603, (1993) (PubMed).

Ashton-Rickardt, Wyllie, Bird, Dunlop, Steel, Morris, Piris, Romanowski, Wood, White: "MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer." in: Oncogene, Vol. 6, Issue 10, pp. 1881-6, (1991) (PubMed).

Kinzler, Nilbert, Vogelstein, Bryan, Levy, Smith, Preisinger, Hamilton, Hedge, Markham: "Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers." in: Science (New York, N.Y.), Vol. 251, Issue 4999, pp. 1366-70, (1991) (PubMed).

Synonyme und alternative Namen zu MCC

mutated in colorectal cancers (MCC), mutated in colorectal cancers (mcc), mutated in colorectal cancers (Mcc), D18Ertd451e, E330037C19, MCC, mcc1, MCC1, RGD1561988

Bezeichner auf Proteinebene für MCC

  • mutated in colorectal cancers
  • colorectal mutant cancer protein
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