MCM10 Produkte
(Minichromosome Maintenance Deficient 10 (MCM10))
Kategorien
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
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Ausgewählte MCM10 Kategorien
MCM10 Antikörper
High quality antibodies with extensive validation data.
MCM10 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MCM10 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6263157
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN949450
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
IF
Validierungen
- (1)
Kat. Nr.
ABIN7261385
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene MCM10 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6211737
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MCM10 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310546
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3093779
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3134892
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MCM10 Produkten
: "Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140645, (2015) (PubMed).: "Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 8, pp. 842-56, (2011) (PubMed).
: "Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication." in: Molecular biology of the cell, Vol. 18, Issue 10, pp. 4085-95, (2007) (PubMed).
: "The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30631-44, (2006) (PubMed).
Synonyme und alternative Namen zu MCM10
Minichromosome maintenance 10 (Mcm10), minichromosome maintenance 10 replication initiation factor (MCM10), minichromosome maintenance 10 replication initiation factor (Mcm10), minichromosome maintenance 10 replication initiation factor L homeolog (mcm10.L), 2410041F14Rik, AU018508, C79164, C330019M07Rik, CG9241, CNA43, Dmel\\CG9241, DmMCM10, DNA43, mcm10, Scim19, xmcm10Bezeichner auf Proteinebene für MCM10
- CG9241-PA
- Mcm10-PA
- sensitized chromosome inheritance modifier 19
- MCM10 minichromosome maintenance deficient 10
- homolog of yeast MCM10
- hsMCM10
- protein MCM10 homolog
- minichromosome maintenance deficient 10
- Mcm10p
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