MCM2 Produkte
(Minichromosome Maintenance Complex Component 2 (MCM2))
Kategorien
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012].
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Ausgewählte MCM2 Kategorien
MCM2 Antikörper
High quality antibodies with extensive validation data.
MCM2 ELISA Kits
Reliable ELISA kits for a wide range of species.
MCM2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MCM2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN969280
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC
Validierungen
- (2)
- (7)
Kat. Nr.
ABIN969281
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IP
Validierungen
- (6)
Kat. Nr.
ABIN561759
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene MCM2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957840
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381301
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN455884
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MCM2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1310547
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5709919
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MCM2 Produkten
: "Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 32, pp. E3325-34, (2014) (PubMed).: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).
: "Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer." in: The Prostate, Vol. 72, Issue 14, pp. 1491-505, (2012) (PubMed).
: "Matrix-embedded endothelial cells are protected from the uremic milieu." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 26, Issue 12, pp. 3858-65, (2011) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 6, pp. 1490-501, (2011) (PubMed).
: "Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA." in: Nucleic acids research, Vol. 39, Issue 12, pp. 5057-66, (2011) (PubMed).
: "Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition." in: The Journal of biological chemistry, Vol. 286, Issue 26, pp. 23031-43, (2011) (PubMed).
: "HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression." in: Cancer research, Vol. 71, Issue 17, pp. 5621-5, (2011) (PubMed).
: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
Synonyme und alternative Namen zu MCM2
Minichromosome maintenance 2 (Mcm2), minichromosome maintenance complex component 2 (mcm2), minichromosome maintenance complex component 2 (MCM2), minichromosome maintenance complex component 2 (Mcm2), minichromosome maintenance complex component 2 L homeolog (mcm2.L), AA959861, AW476101, bm28, BM28, cb737, ccnl1, CCNL1, cdc19, cdcl1, CDCL1, CG7538, chunp6905, D3S3194, dMCM2, Dmel\\CG7538, DmeMCM2, DmMCM2, DmMcm2, l(3)rL074, MCM2, McM2, MCM2-7, MCM2_DROME, MCM7, Mcmd2, mitotin, MITOTIN, mKIAA0030, PCR3, XMcm2Bezeichner auf Proteinebene für MCM2
- CG7538-PA
- Mcm2-PA
- minichromosome maintenance 2
- DNA replication licensing factor mcm2
- MCM2 minichromosome maintenance deficient 2, mitotin
- minichromosome maintenance protein 2
- DNA replication licensing factor MCM2
- cell devision cycle-like 1
- cyclin-like 1
- minichromosome maintenance deficient 2 (mitotin)
- minichromosome maintenance protein 2 homolog
- nuclear protein BM28
- minichromosome maintenance deficient 2 mitotin
- BM28-homolog
- p112
- xMCM2
- minichromosome maintenance complex component 7
- mini chromosome maintenance deficient 2
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