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MCM8 Produkte

(Minichromosome Maintenance Deficient 8 (MCM8))

Kategorien

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte MCM8 Kategorien

MCM8 Antikörper

High quality antibodies with extensive validation data.

MCM8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MCM8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation WB, IHC
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN309831
Menge 25 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN529702
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Bat, Cow, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation WB, IHC, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN6737804
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MCM8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6211736
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MCM8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1310565
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1990369
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505291
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MCM8 Produkten

Inano, Sato, Katsuki, Kobayashi, Tanaka, Nakajima, Nakada, Miyoshi, Knies, Takaori-Kondo, Schindler, Ishiai, Kurumizaka, Takata: "RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination." in: Molecular cell, Vol. 66, Issue 5, pp. 622-634.e8, (2017) (PubMed).

Park, Long, Lee, Abbas, Shibata, Negishi, Luo, Schimenti, Gambus, Walter, Dutta: "The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination." in: Molecular and cellular biology, Vol. 33, Issue 8, pp. 1632-44, (2013) (PubMed).

Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).

Ono, Kumai, Koizumi, Nishikawa, Kobayashi, Tadokoro: "Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues." in: Human pathology, Vol. 40, Issue 1, pp. 41-9, (2008) (PubMed).

Synonyme und alternative Namen zu MCM8

minichromosome maintenance 8 homologous recombination repair factor (MCM8), minichromosome maintenance 8 homologous recombination repair factor (Mcm8), minichromosome maintenance 8 homologous recombination repair factor L homeolog (mcm8.L), 5730432L01Rik, C20orf154, dJ967N21.5

Bezeichner auf Proteinebene für MCM8

  • DNA helicase MCM8
  • DNA replication licensing factor MCM8
  • MCM8 minichromosome maintenance deficient 8
  • REC homolog
  • minichromosome maintenance 8
  • minichromosome maintenance deficient 8
  • Minichromosome maintenance 8
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