Melanophilin Produkte
(Melanophilin (MLPH))
Kategorien
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte Melanophilin Kategorien
Melanophilin Antikörper
High quality antibodies with extensive validation data.
Melanophilin ELISA Kits
Reliable ELISA kits for a wide range of species.
Melanophilin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Melanophilin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7159304
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN7262539
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6263218
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Melanophilin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5592380
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6205901
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Melanophilin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311024
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3083586
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Melanophilin Produkten
: "Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a." in: Journal of cell science, Vol. 132, Issue 9, (2020) (PubMed).: "Identification of immunohistochemical markers for distinguishing lung adenocarcinoma from squamous cell carcinoma." in: Journal of thoracic disease, Vol. 7, Issue 8, pp. 1398-405, (2015) (PubMed).
: "FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast." in: PLoS ONE, Vol. 9, Issue 11, pp. e112024, (2014) (PubMed).
: "Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion." in: The FEBS journal, Vol. 280, Issue 3, pp. 892-903, (2013) (PubMed).
: "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23209-16, (2008) (PubMed).
: "A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes." in: Molecular biology of the cell, Vol. 17, Issue 11, pp. 4720-35, (2006) (PubMed).
: "Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 3, pp. 1215-20, (2003) (PubMed).
: "Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 18, pp. 10238-43, (2001) (PubMed).
: "jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 6, Issue 11, pp. 1437-46, (1996) (PubMed).
: "GS28, a 28-kilodalton Golgi SNARE that participates in ER-Golgi transport." in: Science (New York, N.Y.), Vol. 272, Issue 5265, pp. 1161-3, (1996) (PubMed).
Synonyme und alternative Namen zu Melanophilin
melanophilin (MLPH), melanophilin (mlph), melanophilin (Mlph), 2210418F23Rik, 5031433I09Rik, AW228792, D1Wsu84e, l(1)-3Rk, l1Rk3, ln, LOC100222096, MGC155106, Slac-2a, SLAC2-ABezeichner auf Proteinebene für Melanophilin
- melanophilin
- exophilin-3
- leaden protein
- slaC2-a
- slp homolog lacking C2 domains a
- synaptotagmin-like protein 2a
Haben Sie etwas anderes gesucht?
- Melanoma Marker
- Melanoma Associated Antigen
- Melanoma Antigen Family D, 4B
- Melanoma Antigen Family D, 4
- Melanoma
- Melanocortin 5 Receptor
- MelA
- MEK1/2
- MEK1 + MEK2
- MEK1
- MEIS3P2
- MEIS3P1
- MEIS3
- MEIS1
- Meis Homeobox 2
- Meiotic 41
- Meiosis 1 Associated Protein
- MEIOB
- MEIG1
- MEI4
- Melatonin
- Melatonin Receptor
- Melatonin Receptor 1A
- Melatonin Receptor 1B
- Melatonin Sulfate
- MELC2
- Melittin
- MELK
- Membralin
- Membrane IgA
- Membrane Protein, Palmitoylated 2 (MAGUK P55 Subfamily Member 2)
- Membrane transport protein XK
- Membrane-Spanning 4-Domains, Subfamily A, Member 8
- MEMO1
- menC
- MEND
- Menin
- Meningioma 1
- MEOX1
- MEOX2
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