Merlin Produkte
(Neurofibromin 2 (NF2))
Kategorien
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development\; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008].
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Ausgewählte Merlin Kategorien
Merlin Antikörper
High quality antibodies with extensive validation data.
Merlin ELISA Kits
Reliable ELISA kits for a wide range of species.
Merlin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Merlin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (6)
Kat. Nr.
ABIN6144548
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7434395
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7441928
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Merlin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968860
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958099
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380639
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene Merlin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312430
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7504952
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7395359
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Merlin Produkten
: "An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice." in: Cell stem cell, Vol. 21, Issue 1, pp. 91-106.e6, (2018) (PubMed).: "Influence of Membrane Receptor Lateral Diffusion on the Short-Term Depression of Acetylcholine-Induced Current in Helix Neurons." in: Cellular and molecular neurobiology, (2017) (PubMed).
: "Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP." in: Genes & development, Vol. 29, Issue 12, pp. 1285-97, (2015) (PubMed).
: "Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators." in: Development (Cambridge, England), Vol. 140, Issue 16, pp. 3323-34, (2013) (PubMed).
: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).
: "Expression of P2X7 receptor increases in vivo tumor growth." in: Cancer research, Vol. 72, Issue 12, pp. 2957-69, (2012) (PubMed).
: "Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways." in: Molecular cancer therapeutics, (2011) (PubMed).
: "The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals." in: Developmental cell, Vol. 19, Issue 1, pp. 27-38, (2010) (PubMed).
: "Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells." in: Journal of cell science, Vol. 122, Issue Pt 22, pp. 4141-9, (2010) (PubMed).
: "The phosphorylation status of merlin in sporadic vestibular Schwannomas." in: Molecular and cellular biochemistry, Vol. 324, Issue 1-2, pp. 201-6, (2009) (PubMed).
Synonyme und alternative Namen zu Merlin
neurofibromin 2 (NF2), neurofibromin 2 (Nf2), neurofibromin 2a (merlin) (nf2a), neurofibromin 2b (merlin) (nf2b), neurofibromin 2 (merlin) S homeolog (nf2.S), ACN, BANF, merlin, NF2, nf2, NF2a, SCH, zgc:194620, zgc:194631Bezeichner auf Proteinebene für Merlin
- merlin
- moesin-ezrin-radixin like
- moesin-ezrin-radixin-like protein
- moesin-ezrin-radizin-like protein
- neurofibromin 2 (bilateral acoustic neuroma)
- neurofibromin-2
- schwannomerlin
- schwannomin
- neurofibromin 2
- neurofibromatosis 2
- LOW QUALITY PROTEIN: merlin
- neurofibromin 2 (merlin) S homeolog
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