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Mitogen-Activated Protein Kinase Produkte

(Mitogen-Activated Protein Kinase (MAPK))
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the MAPK/ERK cascade. Depending on the cellular context, this cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The the MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. Many of the substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC)\; as well as in the fragmentation of the Golgi apparatus during mitosis. Phosphorylates microtubule-associated protein 2 (MAP2), myelin basic protein (MBP), and Elk-1. Activated by M phase promoting factor (MPF).

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Ausgewählte Mitogen-Activated Protein Kinase Kategorien

Mitogen-Activated Protein Kinase Antikörper

High quality antibodies with extensive validation data.

Mitogen-Activated Protein Kinase ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene Mitogen-Activated Protein Kinase Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt

Applikation WB
Validierungen
Kat. Nr. ABIN2473488
Menge 0.1 mL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
Kat. Nr. ABIN347177
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse, Rat
Applikation WB
Validierungen
Kat. Nr. ABIN5688866
Menge 0.1 mL
Datenblatt Datenblatt

Empfohlene Mitogen-Activated Protein Kinase ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968637
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rabbit
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN775555
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Guinea Pig
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN777520
Menge 96 tests
Datenblatt Datenblatt

Neueste Publikationen zu unseren Mitogen-Activated Protein Kinase Produkten

Cseh, Doma, Baccarini: ""RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway." in: FEBS letters, Vol. 588, Issue 15, pp. 2398-406, (2014) (PubMed).

Tanoue, Nishida: "Molecular recognitions in the MAP kinase cascades." in: Cellular signalling, Vol. 15, Issue 5, pp. 455-62, (2003) (PubMed).

Johnson, Lapadat: "Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases." in: Science (New York, N.Y.), Vol. 298, Issue 5600, pp. 1911-2, (2002) (PubMed).

Adams, Sweatt: "Molecular psychology: roles for the ERK MAP kinase cascade in memory." in: Annual review of pharmacology and toxicology, Vol. 42, pp. 135-63, (2002) (PubMed).

Synonyme und alternative Namen zu Mitogen-Activated Protein Kinase

mitogen-activated protein kinase (Tc00.1047053506229.10), mitogen-activated protein kinase (Tb927.6.1780), mitogen-activated protein kinase (Tb927.8.3770), mitogen-activated protein kinase 1 S homeolog (mapk1.S), erk, erk2, ert1, mapk, mapk1, mapk1a, mapk2, mpk1, p42mapk, prkm1, prkm2, Tb06.28P18.710, Tb08.10J17.560, xp42

Bezeichner auf Proteinebene für Mitogen-Activated Protein Kinase

  • mitogen-activated protein kinase
  • MAP kinase
  • mitogen-activated protein kinase 1a
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