Mre11 Produkte
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
Kategorien
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog\; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte Mre11 Kategorien
Mre11 Antikörper
High quality antibodies with extensive validation data.
Mre11 ELISA Kits
Reliable ELISA kits for a wide range of species.
Mre11 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Mre11 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (3)
- (4)
Kat. Nr.
ABIN3016250
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Chicken, Hamster, Human, Mouse, Rat
Applikation
WB, IHC, IF, IP, ICC, FACS, ChIP
Validierungen
- (5)
Kat. Nr.
ABIN363310
Menge
0.05 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7443944
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Mre11 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380501
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene Mre11 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1311266
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7402070
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2726317
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Mre11 Produkten
: "MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining." in: Molecular cell, Vol. 71, Issue 2, pp. 332-342.e8, (2019) (PubMed).: "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination." in: Nature communications, Vol. 9, Issue 1, pp. 3872, (2019) (PubMed).
: "Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation." in: Nucleic acids research, Vol. 47, Issue 8, pp. 4068-4085, (2019) (PubMed).
: "UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. ..." in: Cell, Vol. 176, Issue 3, pp. 505-519.e22, (2019) (PubMed).
: "PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis." in: Cell reports, Vol. 26, Issue 5, pp. 1333-1343.e7, (2019) (PubMed).
: "Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription." in: Nucleic acids research, Vol. 47, Issue 13, pp. 6811-6825, (2019) (PubMed).
: "C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex." in: Molecular cell, (2019) (PubMed).
: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." in: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).
: "Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin." in: Marine drugs, Vol. 17, Issue 3, (2019) (PubMed).
: "Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223." in: Cancers, Vol. 11, Issue 12, (2019) (PubMed).
Synonyme und alternative Namen zu Mre11
MRE11 homolog A, double strand break repair nuclease (mre11a), MRE11 homolog, double strand break repair nuclease (MRE11), MRE11A homolog A, double strand break repair nuclease (Mre11a), MRE11 homolog A, double strand break repair nuclease (Mre11a), ATLD, HNGS1, Mre11, MRE11, Mre11b, MRE11B, wu:faa63d12, zgc:64018Bezeichner auf Proteinebene für Mre11
- meiotic recombination 11 homolog A
- MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- MRE11 homolog 1
- MRE11 homolog A
- double-strand break repair protein MRE11A
- meiotic recombination 11 homolog 1
- mmMRE11A
- AT-like disease
- DNA recombination and repair protein
- endo/exonuclease Mre11
- meiotic recombination 11-like protein
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