MRPS12 Produkte
(Mitochondrial Ribosomal Protein S12 (MRPS12))
Kategorien
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene\; all three variants encode the same protein. [provided by RefSeq, Jul 2008].
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Ausgewählte MRPS12 Kategorien
MRPS12 Antikörper
High quality antibodies with extensive validation data.
MRPS12 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MRPS12 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN7187367
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, ICC, IF
Validierungen
- (2)
Kat. Nr.
ABIN6257348
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN656569
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene MRPS12 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311353
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Dictyostelium sp.
Source
Yeast
Validierungen
Kat. Nr.
ABIN1659673
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MRPS12 Produkten
: "Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma." in: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 395-402, (2000) (PubMed).: "Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity." in: Annual review of immunology, Vol. 18, Issue 8, pp. 621-63, (2000) (PubMed).
Synonyme und alternative Namen zu MRPS12
mitochondrial ribosomal protein S12 (MRPS12), mitochondrial ribosomal protein S12 (Mrps12), technical knockout (tko), mitochondrial ribosomal protein S12 L homeolog (mrps12.L), 40S ribosomal protein S12, mitochondrial (LOC409723), mitochondrial ribosomal protein S12 (mRpS12), mitochondrial ribosomal protein S12 (mrps12), putative mitochondrial 37S ribosomal protein MRPS12 (MRPS12), putative mitochondrial 37S ribosomal protein MRPS12 (CAALFM_C106070WA), mitochondrial ribosomal protein S12 (mrpS12), fragile site, aphidicolin type, common, fra(6)(p22.2) (FRA6C), AI327385, CG7925, Dmel\\CG7925, EG:BACH59J11.1, GB10531, l(1)3Ab, l(1)tko, MGC64304, MPR-S12, MRP-S12, MRPS12, mRpS12, MT-RPS12, mt-rps12, RPMS12, Rpms12, RPS12, rps12, RPSM12, S12, TkoBezeichner auf Proteinebene für MRPS12
- 28S ribosomal protein S12, mitochondrial
- MRP-S12
- S12mt
- MT-RPS12
- mitoribosomal protein s12
- ribosomal protein, mitochondrial, S12
- CG7925-PB
- CG7925-PC
- mitochondrial ribosomal protein S12
- mitoribosomal protein S12
- tko-PB
- tko-PC
- Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins
- Mrps12p
- likely mitochondrial ribosomal protein S12
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