MUTYH Produkte
(MutY Homolog (E. Coli) (MUTYH))
Kategorien
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte MUTYH Kategorien
MUTYH Antikörper
High quality antibodies with extensive validation data.
MUTYH ELISA Kits
Reliable ELISA kits for a wide range of species.
MUTYH Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MUTYH Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP, RNAi
Validierungen
- (7)
- (6)
Kat. Nr.
ABIN561883
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN3187926
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, FACS
Validierungen
- (3)
Kat. Nr.
ABIN653106
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene MUTYH ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957923
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1742632
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1773536
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MUTYH Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311668
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311667
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7399868
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MUTYH Produkten
: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).: "MUTYH and ORAI1 polymorphisms are associated with susceptibility to osteoarthritis in the Chinese Han population." in: The Journal of international medical research, Vol. 46, Issue 6, pp. 2292-2300, (2019) (PubMed).
: "Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis." in: Oncotarget, Vol. 8, Issue 20, pp. 32752-32768, (2017) (PubMed).
: "Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain." in: Human mutation, Vol. 36, Issue 7, pp. 704-11, (2015) (PubMed).
: "Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer." in: Oxidative medicine and cellular longevity, Vol. 2014, pp. 617351, (2014) (PubMed).
: "Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation." in: BMC molecular biology, Vol. 15, pp. 17, (2014) (PubMed).
: "Understanding the role of the Q338H MUTYH variant in oxidative damage repair." in: Nucleic acids research, Vol. 41, Issue 7, pp. 4093-103, (2013) (PubMed).
: "Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells." in: Carcinogenesis, Vol. 33, Issue 11, pp. 2301-9, (2012) (PubMed).
: "Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells." in: Oncology letters, Vol. 4, Issue 6, pp. 1203-1208, (2012) (PubMed).
: "p73 protein regulates DNA damage repair." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 12, pp. 4406-14, (2011) (PubMed).
Synonyme und alternative Namen zu MUTYH
mutY DNA glycosylase (MUTYH), mutY homolog (E. coli) (MUTYH), mutY DNA glycosylase (mutyh), A/G-specific adenine DNA glycosylase-like (LOC100373318), mutY DNA glycosylase (Mutyh), 5730495A01Rik, CYP2C, MGC145569, MUTYH, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, MYH, MyhBezeichner auf Proteinebene für MUTYH
- mutY homolog (E. coli)
- A/G-specific adenine DNA glycosylase
- A/G-specific adenine DNA glycosylase-like
- mutY homolog
- adenine-DNA glycosylase
- mMYH
- mutY homolog alpha
- the full-length form type A, 5' region
- rMYH
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