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MUTYH Produkte

(MutY Homolog (E. Coli) (MUTYH))

Kategorien

This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte MUTYH Kategorien

MUTYH Antikörper

High quality antibodies with extensive validation data.

MUTYH ELISA Kits

Reliable ELISA kits for a wide range of species.

MUTYH Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MUTYH Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP, RNAi
Validierungen
  • (7)
  • (6)
Kat. Nr. ABIN561883
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN3187926
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, FACS
Validierungen
  • (3)
Kat. Nr. ABIN653106
Menge 400 μL
Datenblatt Datenblatt

Empfohlene MUTYH ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6957923
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1742632
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Sheep
Analytical Method
Validierungen
Kat. Nr. ABIN1773536
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MUTYH Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311668
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311667
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7399868
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MUTYH Produkten

Ferreira, Rosa Soares, Ramalho, Ribeiro-Rodrigues, Máximo, Zuzarte, Girão, Pereira: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).

Zhang, Guo, Chen, Chen, Jin: "MUTYH and ORAI1 polymorphisms are associated with susceptibility to osteoarthritis in the Chinese Han population." in: The Journal of international medical research, Vol. 46, Issue 6, pp. 2292-2300, (2019) (PubMed).

Fang, Ohman Strickland, Kang, Zarbl: "Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis." in: Oncotarget, Vol. 8, Issue 20, pp. 32752-32768, (2017) (PubMed).

Komine, Shimodaira, Takao, Soeda, Zhang, Takahashi, Ishioka: "Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain." in: Human mutation, Vol. 36, Issue 7, pp. 704-11, (2015) (PubMed).

Shinmura, Goto, Tao, Kato, Suzuki, Nakamura, Matsuda, Yin, Morita, Kono, Sugimura: "Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer." in: Oxidative medicine and cellular longevity, Vol. 2014, pp. 617351, (2014) (PubMed).

Agustina, Hahm, Han, Tran, Chung, Park, Park, Han: "Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation." in: BMC molecular biology, Vol. 15, pp. 17, (2014) (PubMed).

Turco, Ventura, Minoprio, Russo, Torreri, Degan, Molatore, Ranzani, Bignami, Mazzei: "Understanding the role of the Q338H MUTYH variant in oxidative damage repair." in: Nucleic acids research, Vol. 41, Issue 7, pp. 4093-103, (2013) (PubMed).

Raetz, Xie, Kundu, Brinkmeyer, Chang, David: "Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells." in: Carcinogenesis, Vol. 33, Issue 11, pp. 2301-9, (2012) (PubMed).

Hahm, Chung, Agustina, Han, Yoon, Park, Kang, Park, Na, Han: "Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells." in: Oncology letters, Vol. 4, Issue 6, pp. 1203-1208, (2012) (PubMed).

Zaika, Wei, Yin, Andl, Moll, El-Rifai, Zaika: "p73 protein regulates DNA damage repair." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 12, pp. 4406-14, (2011) (PubMed).

Synonyme und alternative Namen zu MUTYH

mutY DNA glycosylase (MUTYH), mutY homolog (E. coli) (MUTYH), mutY DNA glycosylase (mutyh), A/G-specific adenine DNA glycosylase-like (LOC100373318), mutY DNA glycosylase (Mutyh), 5730495A01Rik, CYP2C, MGC145569, MUTYH, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, MYH, Myh

Bezeichner auf Proteinebene für MUTYH

  • mutY homolog (E. coli)
  • A/G-specific adenine DNA glycosylase
  • A/G-specific adenine DNA glycosylase-like
  • mutY homolog
  • adenine-DNA glycosylase
  • mMYH
  • mutY homolog alpha
  • the full-length form type A, 5' region
  • rMYH
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