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MYCN Produkte

(N-Myc Proto-Oncogene Protein (MYCN))

Kategorien

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008].

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Ausgewählte MYCN Kategorien

MYCN Antikörper

High quality antibodies with extensive validation data.

MYCN ELISA Kits

Reliable ELISA kits for a wide range of species.

MYCN Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MYCN Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (3)
  • (1)
Kat. Nr. ABIN760676
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN1680957
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (6)
Kat. Nr. ABIN7193585
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MYCN ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6974813
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5591497
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN2870005
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MYCN Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN1311728
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124095
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311730
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MYCN Produkten

Cheng, He, Chen, Cai, Gu, Pan, Duan, Wu, Wu: "P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma." in: Molecular & cellular proteomics : MCP, Vol. 22, Issue 3, pp. 100504, (2023) (PubMed).

Murakami-Tonami, Ikeda, Yamagishi, Inayoshi, Inagaki, Kishida, Komata, Jan Koster, Takeuchi, Kondo, Maeda, Sekido, Murakami, Kadomatsu: "SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells." in: Scientific reports, Vol. 6, pp. 31615, (2016) (PubMed).

Ramraj, Aravindan, Somasundaram, Herman, Natarajan, Aravindan: "Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease." in: Oncotarget, Vol. 7, Issue 14, pp. 18605-19, (2016) (PubMed).

Chang, Yang, Zheng, Li, Nie: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).

Li, Sun, Chen, Squires, Nowroozizadeh, Liang, Huang: "p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma." in: Molecular cancer research : MCR, Vol. 13, Issue 3, pp. 584-91, (2015) (PubMed).

Smith, Moreno, Heaton, Chesler, Pearson, Garrett: "Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma." in: Molecular oncology, (2015) (PubMed).

Ruiz-Pérez, Medina, Urdiales, Keinänen, Sánchez-Jiménez: "Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells." in: The Journal of biological chemistry, Vol. 290, Issue 10, pp. 6106-19, (2015) (PubMed).

Yang, AlTahan, Hu, Wang, Cheng, Morton, Qu, Nathwani, Shohet, Fotsis, Koster, Versteeg, Okada, Harris, Davidoff: "The role of histone demethylase KDM4B in Myc signaling in neuroblastoma." in: Journal of the National Cancer Institute, Vol. 107, Issue 6, pp. djv080, (2015) (PubMed).

Suenaga, Islam, Alagu, Kaneko, Kato, Tanaka, Kawana, Hossain, Matsumoto, Yamamoto, Shoji, Itami, Shibata, Nakamura, Ohira, Haraguchi, Takatori, Nakagawara: "NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3? resulting in the stabilization of MYCN in human neuroblastomas." in: PLoS genetics, Vol. 10, Issue 1, pp. e1003996, (2014) (PubMed).

Murakami-Tonami, Kishida, Takeuchi, Katou, Maris, Ichikawa, Kondo, Sekido, Shirahige, Murakami, Kadomatsu: "Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells." in: Cell cycle (Georgetown, Tex.), Vol. 13, Issue 7, pp. 1115-31, (2014) (PubMed).

Synonyme und alternative Namen zu MYCN

MYCN proto-oncogene, bHLH transcription factor (MYCN), v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Mycn), MYCN proto-oncogene, bHLH transcription factor (Mycn), olfactory receptor 8S1 (LOC515887), MYCN proto-oncogene, bHLH transcription factor (mycn), MYCN proto-oncogene, bHLH transcription factor S homeolog (mycn.S), bHLHe37, c-nmyc, fb57a02, MODED, mycn, mycn-a, mycn-b, mycna, MYCNOT, N-myc, Nmuc1, NMYC, Nmyc, Nmyc-1, Nmyc1, nmyc1, ODED, wu:fb57a02, XN-myc, xN-myc1, XNmyc, zgc:85706

Bezeichner auf Proteinebene für MYCN

  • N-myc proto-oncogene protein
  • class E basic helix-loop-helix protein 37
  • neuroblastoma MYC oncogene
  • neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
  • oncogene NMYC
  • pp65/67
  • v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
  • N-myc protein
  • neuroblastoma myc-related oncogene 1
  • Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc)
  • Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc)
  • N-myc-like protein
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
  • MYCN proto-oncogene, bHLH transcription factor S homeolog
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog S homeolog
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived, a
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