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Nanog Produkte

(Nanog Homeobox (NANOG))
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

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Ausgewählte Nanog Kategorien

Nanog Antikörper

High quality antibodies with extensive validation data.

Nanog ELISA Kits

Reliable ELISA kits for a wide range of species.

Nanog Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Nanog Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC, ICC, IHC (p), IP, IHC (fro)
Validierungen
  • (6)
  • (14)
Kat. Nr. ABIN2854880
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN2177828
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, FACS, ICC
Validierungen
  • (9)
Kat. Nr. ABIN7155816
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Nanog ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968797
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958029
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validierungen
  • (2)
Kat. Nr. ABIN5526712
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Nanog Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124111
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN667504
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2565285
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Nanog Produkten

Wang, Jing, Hu, Yu, Yao, Li, Cheng: "Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma." in: Journal of cellular and molecular medicine, (2021) (PubMed).

Tan, Xu, Du, Wu, Guo, Huang, Zhu, Li, Lin, Yao: "SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG." in: Cell death & disease, Vol. 10, Issue 11, pp. 794, (2020) (PubMed).

Moreno-Marín, Barrasa, Morales-Hernández, Paniagua, Blanco-Fernández, Merino, Fernández-Salguero: "Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis." in: Scientific reports, Vol. 7, Issue 1, pp. 10420, (2019) (PubMed).

Ahmed, El-Sayed, Chen, Zhao, Jin, Zuo, Zhang, Li: "Direct conversion of mouse embryonic fibroblast to osteoblast cells using hLMP-3 with Yamanaka factors." in: The international journal of biochemistry & cell biology, Vol. 106, pp. 84-95, (2019) (PubMed).

He, Wang, Zhang, Chen, Liang, Li, Zhang, Yang, Pang, Li, Huang, Qin, Pei, Sun, Zheng: "Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming." in: Cell discovery, Vol. 5, pp. 11, (2019) (PubMed).

Castelli, Susani, Menale, Muggeo, Caldana, Strina, Cassani, Recordati, Scanziani, Ficara, Villa, Vezzoni, Paulis: "Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells." in: Stem cells (Dayton, Ohio), Vol. 37, Issue 7, pp. 876-887, (2019) (PubMed).

Kodama, Harinath, Mihara-Tomiyama, Tominaga, Ide, Nakahara, Maeda, Igarashi, DArmiento, Chada, Imai: "Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression." in: Biochemical and biophysical research communications, Vol. 509, Issue 4, pp. 1008-1014, (2019) (PubMed).

Glennon, Austin, Arang, Kain, Mast, Vijayan, Aitchison, Kappe, Kaushansky: "Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection." in: Cell reports, Vol. 26, Issue 12, pp. 3391-3399.e4, (2019) (PubMed).

Daum, Brauchle, Berrio, Jurkowski, Schenke-Layland: "Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging." in: Scientific reports, Vol. 9, Issue 1, pp. 7014, (2019) (PubMed).

Nasr, Farghaly, Elsaba, El-Mokhtar, Radwan, Elsabahy, Abdelkareem, Fakhry, Mousa: "Resistance of primary breast cancer cells with enhanced pluripotency and stem cell activity to sex hormonal stimulation and suppression." in: The international journal of biochemistry & cell biology, Vol. 105, pp. 84-93, (2019) (PubMed).

Synonyme und alternative Namen zu Nanog

Nanog homeobox (Nanog), Nanog homeobox (NANOG), nanog homeobox (nanog), 2410002E02Rik, ecat4, ENK, hacp, NANOG, wu:fd19e04, wu:fd20a07, zgc:193933

Bezeichner auf Proteinebene für Nanog

  • ES cell-associated protein 4
  • early embryo specific expression NK family
  • early embryo specific expression NK-type homeobox protein
  • homeobox protein NANOG
  • homeobox transcription factor Nanog
  • hNanog
  • homeobox transcription factor Nanog-delta 48
  • homeobox transcription factor NANOG
  • Nanog homeobox
  • nanog homeobox transcription factor
  • homeodomain transcription factor Nanog
  • LOW QUALITY PROTEIN: homeobox protein NANOG
  • fd20a07
  • nanog homeobox
  • ovary-expressed homeobox protein
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