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NCF2 Produkte

(Neutrophil Cytosolic Factor 2 (NCF2))

Kategorien

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010].

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Ausgewählte NCF2 Kategorien

NCF2 Antikörper

High quality antibodies with extensive validation data.

NCF2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NCF2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NCF2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN7161498
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN6263535
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (4)
Kat. Nr. ABIN3021641
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NCF2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958175
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951326
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NCF2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312095
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312097
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7415524
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NCF2 Produkten

Li, Meng, Zhang, Wang, Yang, Niu, Cui, Wang, Liu, Rao: "Testosterone improves erectile function through inhibition of reactive oxygen species generation in castrated rats." in: PeerJ, Vol. 4, pp. e2000, (2016) (PubMed).

Lomnytska, Becker, Bodin, Olsson, Hellman, Hellström, Mints, Hellman, Auer, Andersson: "Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value." in: British journal of cancer, Vol. 104, Issue 1, pp. 110-9, (2011) (PubMed).

Ago, Nunoi, Ito, Sumimoto: "Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating" in: The Journal of biological chemistry, Vol. 274, Issue 47, pp. 33644-53, (1999) (PubMed).

Benna, Dang, Gaudry, Fay, Morel, Hakim, Gougerot-Pocidalo: "Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways." in: The Journal of biological chemistry, Vol. 272, Issue 27, pp. 17204-8, (1997) (PubMed).

Freeman, Lambeth: "NADPH oxidase activity is independent of p47phox in vitro." in: The Journal of biological chemistry, Vol. 271, Issue 37, pp. 22578-82, (1996) (PubMed).

Leto, Adams, de Mendez: "Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 22, pp. 10650-4, (1994) (PubMed).

Leto, Lomax, Volpp, Nunoi, Sechler, Nauseef, Clark, Gallin, Malech: "Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src." in: Science (New York, N.Y.), Vol. 248, Issue 4956, pp. 727-30, (1990) (PubMed).

Synonyme und alternative Namen zu NCF2

neutrophil cytosolic factor 2 (NCF2), neutrophil cytosolic factor 2 L homeolog (ncf2.L), neutrophil cytosolic factor 2 (ncf2), neutrophil cytosolic factor 2 (p67phox), neutrophil cytosol factor 2 (VDBG_06643), hypothetical protein (PGTG_05816), neutrophil cytosolic factor 2 (LOC100136240), neutrophil cytosolic factor 2 (Ncf2), MGC81877, NCF-2, Ncf-2, noxa2, NOXA2, p67-phox, P67-PHOX, p67phox, P67PHOX, zgc:158405

Bezeichner auf Proteinebene für NCF2

  • neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)
  • neutrophil cytosolic factor 2
  • neutrophil cytosol factor 2
  • predicted neutrophil cytosolic factor 2
  • p67phox
  • p67-phox
  • NADPH oxidase cytosolic protein p67phox
  • NADPH oxidase cytosolic protein
  • 67 kDa neutrophil oxidase factor
  • NADPH oxidase activator 2
  • chronic granulomatous disease, autosomal 2
  • neutrophil NADPH oxidase factor 2
  • neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
  • NADPH oxidase subunit (67 kD)
  • NADPH oxidase subunit (67kDa)
  • NCF-2
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