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NCOA1 Produkte

(Nuclear Receptor Coactivator 1 (NCOA1))
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Ausgewählte NCOA1 Kategorien

NCOA1 Antikörper

High quality antibodies with extensive validation data.

NCOA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NCOA1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NCOA1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (3)
Kat. Nr. ABIN3021492
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN391825
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (2)
Kat. Nr. ABIN7269005
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NCOA1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969007
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969006
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Pig
Analytical Method
Validierungen
Kat. Nr. ABIN1145493
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NCOA1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312124
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7422733
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (1)
Kat. Nr. ABIN2732662
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NCOA1 Produkten

Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: "Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment." in: Cell reports, Vol. 18, Issue 8, pp. 1946-1957, (2017) (PubMed).

Lau, Yang, Chang: "Isoform-selective activation of human constitutive androstane receptor by Ginkgo biloba extract: functional analysis of the SV23, SV24, and SV25 splice variants." in: The Journal of pharmacology and experimental therapeutics, Vol. 339, Issue 2, pp. 704-15, (2011) (PubMed).

Lau, Yang, Rajaraman, Baucom, Chang: "Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor." in: The Journal of pharmacology and experimental therapeutics, Vol. 336, Issue 3, pp. 816-26, (2011) (PubMed).

Lau, Yang, Rajaraman, Baucom, Chang: "Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides." in: The Journal of pharmacology and experimental therapeutics, Vol. 335, Issue 3, pp. 771-80, (2010) (PubMed).

Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: "Androgen modulation of coregulator expression in prostate cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).

Privalsky, Lee, Hahm, Young, Fong, Chan: "The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 284, Issue 29, pp. 19554-63, (2009) (PubMed).

Amita, Takahashi, Tsutsumi, Ohta, Takata, Henmi, Hara, Igarashi, Takahashi, Kurachi: "Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate." in: Endocrinology, Vol. 151, Issue 1, pp. 394-405, (2009) (PubMed).

Lavery, McEwan: "Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a." in: Biochemistry, Vol. 47, Issue 11, pp. 3352-9, (2008) (PubMed).

Wang, Zhang, Nordeen, Shapiro: "In vitro fluorescence anisotropy analysis of the interaction of full-length SRC1a with estrogen receptors alpha and beta supports an active displacement model for coregulator utilization." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2765-75, (2007) (PubMed).

Jaber, Gao, Huang, Karmakar, Smith et al.: "The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2695-710, (2006) (PubMed).

Synonyme und alternative Namen zu NCOA1

nuclear receptor coactivator 1 (NCOA1), nuclear receptor coactivator 1 (ncoa1), nuclear receptor coactivator 1 (Ncoa1), bHLHe42, bHLHe74, F-SRC-1, KAT13A, NCOA1, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRC-1, SRC1

Bezeichner auf Proteinebene für NCOA1

  • Hin-2 protein
  • PAX3/NCOA1 fusion protein
  • class E basic helix-loop-helix protein 74
  • renal carcinoma antigen NY-REN-52
  • steroid receptor coactivator-1
  • nuclear receptor coactivator 1
  • steroid receptor coactivator 1
  • DKEY-34F16.7
  • SRC1
  • NCoA-1
  • SRC-a/NCoA-1
  • mNRC-1
  • nuclear receptor coactivator protein 1
  • SRC-1
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