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NDC80 Produkte

(NDC80 Kinetochore Complex Component Homolog (NDC80))

Kategorien

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011].

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Ausgewählte NDC80 Kategorien

NDC80 Antikörper

High quality antibodies with extensive validation data.

NDC80 ELISA Kits

Reliable ELISA kits for a wide range of species.

NDC80 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NDC80 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN564521
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6263548
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN184821
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NDC80 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648262
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NDC80 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312158
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312160
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3137068
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NDC80 Produkten

Raab, Sanhaji, Matthess, Hörlin, Lorenz, Dötsch, Habbe, Waidmann, Kurunci-Csacsko, Firestein, Becker, Strebhardt: "PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells." in: Nature communications, Vol. 9, Issue 1, pp. 1106, (2018) (PubMed).

DeLuca, Meppelink, Broad, Mick, Peersen, Pektas, Lens, DeLuca: "Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics." in: The Journal of cell biology, Vol. 217, Issue 1, pp. 163-177, (2018) (PubMed).

Dumitru, Rusin, Clark, Kettenbach, Compton: "Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability." in: eLife, Vol. 6, (2017) (PubMed).

Tauchman, Boehm, DeLuca: "Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells." in: Nature communications, Vol. 6, pp. 10036, (2015) (PubMed).

Yao, Kondoh, Natsume, Yamanaka, Inoue, Toki, Takagi, Shimizu, Yamori, Osada, Noda: "A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells." in: Oncogene, Vol. 33, Issue 33, pp. 4242-52, (2014) (PubMed).

Sivakumar, Daum, Tipton, Rankin, Gorbsky: "The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit." in: Molecular biology of the cell, Vol. 25, Issue 5, pp. 594-605, (2014) (PubMed).

Kleyman, Kabeche, Compton: "STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments." in: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4225-33, (2014) (PubMed).

Hwang, Peddibhotla, McHenry, Chang, Yochum, Park, Sears, Vargo-Gogola: "P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells." in: Cancers, Vol. 4, Issue 2, pp. 475-89, (2013) (PubMed).

Maier, Kirsch, Anderhub, Zentgraf, Krämer: "The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 9, pp. 1457-71, (2013) (PubMed).

Kabeche, Compton: "Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation." in: Nature, Vol. 502, Issue 7469, pp. 110-3, (2013) (PubMed).

Synonyme und alternative Namen zu NDC80

NDC80, kinetochore complex component (NDC80), CG9938 gene product from transcript CG9938-RA (Ndc80), spindle pole body protein Ndc80 (ndc80), kinetochore protein Ndc80 (ndc80), NDC80 homolog, kinetochore complex component (S. cerevisiae) (ndc80), NDC80 kinetochore complex component (Ndc80), NDC80 kinetochore complex component (ndc80), NDC80 kinetochore complex component S homeolog (ndc80.S), 2610020P18Rik, AV139730, CG9938, Dmel\\CG9938, dmNdc80, dNdc80, HEC, Hec1, hec1, HEC1, HsHec1, hsNDC80, KNTC2, Kntc2, kntc2, kntc2l, ndc10, NDC80, tid3, TID3, wu:fb52e02, zgc:111801

Bezeichner auf Proteinebene für NDC80

  • kinetochore associated 2
  • CG9938-PA
  • Hec1
  • Ndc80-PA
  • NDC80 homolog, kinetochore complex component (S. cerevisiae)
  • NDC80 homolog, kinetochore complex component
  • kinetochore protein NDC80 homolog
  • kinetochore protein Ndc80
  • Kinetochore protein NDC80 homolog
  • highly expressed in cancer, rich in leucine heptad repeats
  • kinetochore protein Hec1
  • kinetochore-associated protein 2
  • HEC (highly expressed in cancer)
  • NDC80 kinetochore complex component homolog
  • highly expressed in cancer protein
  • retinoblastoma-associated protein HEC
  • kinetochore spindle checkpoint protein Ndc80
  • xNdc80
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