NEDD9 Produkte
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
Kategorien
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Ausgewählte NEDD9 Kategorien
NEDD9 Antikörper
High quality antibodies with extensive validation data.
NEDD9 ELISA Kits
Reliable ELISA kits for a wide range of species.
NEDD9 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NEDD9 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (9)
Kat. Nr.
ABIN3023331
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN129518
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN561951
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene NEDD9 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968848
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1131949
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NEDD9 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312332
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312334
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3090359
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NEDD9 Produkten
: "Overexpression of NEDD9 promotes cell invasion and metastasis in hepatocellular carcinoma." in: Clinics and research in hepatology and gastroenterology, Vol. 41, Issue 6, pp. 677-686, (2018) (PubMed).: "Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability." in: Immunology and cell biology, Vol. 94, Issue 10, pp. 981-993, (2016) (PubMed).
: "NEDD9 overexpression correlates with poor prognosis in gastric cancer." in: Tumour biology, Vol. 35, Issue 7, pp. 6351-6, (2014) (PubMed).
: "The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway." in: Oncogene, Vol. 32, Issue 14, pp. 1811-20, (2013) (PubMed).
: "The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC." in: PLoS ONE, Vol. 8, Issue 9, pp. e74594, (2013) (PubMed).
: "NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration." in: PLoS ONE, Vol. 7, Issue 4, pp. e35058, (2012) (PubMed).
: "Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation." in: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21526-36, (2010) (PubMed).
: "Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. ..." in: Human molecular genetics, Vol. 17, Issue 5, pp. 759-67, (2008) (PubMed).
: "Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene." in: Cell, Vol. 125, Issue 7, pp. 1269-81, (2006) (PubMed).
: "The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking." in: Immunity, Vol. 25, Issue 6, pp. 907-18, (2006) (PubMed).
Synonyme und alternative Namen zu NEDD9
neural precursor cell expressed, developmentally down-regulated 9 (NEDD9), neural precursor cell expressed, developmentally down-regulated 9 (Nedd9), neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), CAS-L, Cas-L, CAS2, CASL, CasL, CASS2, E230025G09Rik, HEF1, NEDD9Bezeichner auf Proteinebene für NEDD9
- neural precursor cell expressed, developmentally down-regulated 9
- enhancer of filamentation 1 homolog
- Cas scaffolding protein family member 2
- Crk-associated substrate related protein Cas-L
- Enhancer of filamentation 1 p55
- cas-like docking
- enhancer of filamentation 1
- neural precursor cell expressed developmentally down-regulated protein 9
- p130Cas-related protein
- renal carcinoma antigen NY-REN-12
- neural precursor cell expressed, developmentally down-regulated gene 9
- CRK-associated substrate-related protein
- Crk-associated substrate lymphocyte-specific protein
- NEDD-9
- mEF1
- p105
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