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NEK2 Produkte

(NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))

Kategorien

This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011].

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Ausgewählte NEK2 Kategorien

NEK2 Antikörper

High quality antibodies with extensive validation data.

NEK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NEK2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NEK2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7439456
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN561955
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN561956
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NEK2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5525181
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NEK2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312356
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509038
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7416697
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NEK2 Produkten

Zhao, Han, Liu, Cui, Chen: "MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2." in: Thoracic cancer, Vol. 8, Issue 4, pp. 304-311, (2018) (PubMed).

Lin, Zhou, Jiang, Liu, Wang, Zheng, Zhou, Li, Cai: "NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma." in: Oncology reports, Vol. 36, Issue 2, pp. 853-62, (2017) (PubMed).

Zeng, Han, Wang, Cai, Huang, Luo, Liu, Zhuo, Dai, Zhao, Liang, Zhong: "Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer." in: BMC urology, Vol. 15, pp. 90, (2015) (PubMed).

Zhong, Guan, Dong, Yang, Liu, Zhang: "Examining Nek2 as a better proliferation marker in non-small cell lung cancer prognosis." in: Tumour biology, Vol. 35, Issue 7, pp. 7155-62, (2014) (PubMed).

Zhong, Guan, Liu, Zhang: "Aberrant expression of NEK2 and its clinical significance in non-small cell lung cancer." in: Oncology letters, Vol. 8, Issue 4, pp. 1470-1476, (2014) (PubMed).

Naro, Barbagallo, Chieffi, Bourgeois, Paronetto, Sette: "The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival." in: Nucleic acids research, Vol. 42, Issue 5, pp. 3218-27, (2014) (PubMed).

Jeong, Lee, Park, Han, Jang, Lim, Lee, Yang: "Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 28-40, (2014) (PubMed).

van Ree, Jeganathan, Malureanu, van Deursen: "Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation." in: The Journal of cell biology, Vol. 188, Issue 1, pp. 83-100, (2010) (PubMed).

Barbagallo, Paronetto, Franco, Chieffi, Dolci, Fry, Geremia, Sette: "Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas." in: The Journal of pathology, Vol. 217, Issue 3, pp. 431-41, (2009) (PubMed).

Wu, Baxter, Wattam, Hayward, Fardilha, Knebel, Ford, da Cruz e Silva, Fry: "Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26431-40, (2007) (PubMed).

Synonyme und alternative Namen zu NEK2

NIMA related kinase 2 (NEK2), NIMA (never in mitosis gene a)-related expressed kinase 2 (Nek2), NIMA-related kinase 2 (Nek2), NIMA-related kinase 2 (NEK2), AA617254, ATNEK2, C77054, HsPK21, NEK2A, NIMA-RELATED KINASE2, NIMA-related kinase 2, NLK1, T9J14.24, T9J14_24

Bezeichner auf Proteinebene für NEK2

  • NIMA (never in mitosis gene a)-related kinase 2
  • NIMA - related expressed kinase 2
  • NIMA-related expressed kinase 2
  • NIMA-related kinase 2
  • Nek2 kinase
  • never in mitosis A-related kinase 2
  • nimA-related protein kinase 2
  • serine/threonine-protein kinase Nek2
  • serine/threonine protein kinase Nek2
  • nimA-like protein kinase 1
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