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NEU1 Produkte

(Sialidase 1 (Lysosomal Sialidase) (NEU1))
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008].

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Ausgewählte NEU1 Kategorien

NEU1 Antikörper

High quality antibodies with extensive validation data.

NEU1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NEU1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NEU1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (9)
Kat. Nr. ABIN7438058
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IHC (p)
Validierungen
  • (9)
Kat. Nr. ABIN1491548
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (5)
Kat. Nr. ABIN1774878
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NEU1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6973751
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5518637
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN511750
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NEU1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125087
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312399
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN3084304
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NEU1 Produkten

Demir, Özcan, Balat, Öztürk, Uğur, Gündüz, Taysi: "Assessment of total sialic acid levels in patients with hyperemesis gravidarum: a preliminary study." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 38, Issue 4, pp. 532-535, (2018) (PubMed).

Luzina, Lockatell, Hyun, Kopach, Kang, Noor, Liu, Lillehoj, Lee, Miranda-Ribera, Todd, Goldblum, Atamas: "Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 310, Issue 10, pp. L940-54, (2017) (PubMed).

Hyun, Liu, Liu, Cross, Verceles, Magesh, Kommagalla, Kona, Ando, Luzina, Atamas, Piepenbrink, Sundberg, Guang, Ishida, Lillehoj, Goldblum: "The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo." in: Glycobiology, Vol. 26, Issue 8, pp. 834-49, (2016) (PubMed).

Li, Ma, Sarker, McClane: "CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718." in: mBio, Vol. 4, Issue 5, pp. e00770-13, (2013) (PubMed).

Caciotti, Di Rocco, Filocamo, Grossi, Traverso, dAzzo, Cavicchi, Messeri, Guerrini, Zammarchi, Donati, Morrone: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." in: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).

Lai, Chen, Wu Chou, Chang, Kao, Huang, Weng, Chen, Hwu, Lu: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).

Bonten, Campos, Zaitsev, Nourse, Waddell, Lewis, Taylor, dAzzo: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).

Synonyme und alternative Namen zu NEU1

neuraminidase 1 (NEU1), neuraminidase 1 (lysosomal sialidase) L homeolog (neu1.L), neuraminidase 1 (neu1), neuraminidase 1 (Neu1), AA407268, AA407316, Aglp, Apl, Bat-7, Bat7, G9, Map-2, MGC81958, NANH, NEU, Neu, Neu-1, SIAL1

Bezeichner auf Proteinebene für NEU1

  • G9 sialidase
  • N-acetyl-alpha-neuraminidase 1
  • acetylneuraminyl hydrolase
  • exo-alpha-sialidase
  • lysosomal sialidase
  • sialidase-1
  • sialidase 1 (lysosomal sialidase)
  • neuraminidase
  • isotocin
  • Isotocin-neurophysin IT 1
  • neuraminidase 1
  • sialidase-1-like
  • HLA-B-associated transcript 7
  • sialidase 1
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