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Neuregulin 2 Produkte

(Neuregulin 2 (NRG2))
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010].

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Ausgewählte Neuregulin 2 Kategorien

Neuregulin 2 Antikörper

High quality antibodies with extensive validation data.

Neuregulin 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Neuregulin 2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Neuregulin 2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7074804
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN564118
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7164305
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Neuregulin 2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958087
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958088
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5657249
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Neuregulin 2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313024
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN1330340
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7396007
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Neuregulin 2 Produkten

Frogne, Benjaminsen, Sonne-Hansen, Sorensen, Nexo, Laenkholm, Rasmussen, Riese, de Cremoux, Stenvang, Lykkesfeldt: "Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant." in: Breast cancer research and treatment, Vol. 114, Issue 2, pp. 263-75, (2009) (PubMed).

Yamada, Ichino, Nishii, Sawada, Higashiyama, Ishiguro, Nagatsu: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." in: Gene, Vol. 255, Issue 1, pp. 15-24, (2000) (PubMed).

Ring, Chang, Guilbot, Brice, LeGuern, Francke: "The human neuregulin-2 (NRG2) gene: cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q." in: Human genetics, Vol. 104, Issue 4, pp. 326-32, (1999) (PubMed).

Higashiyama, Horikawa, Yamada, Ichino, Nakano, Nakagawa, Miyagawa, Matsushita, Nagatsu, Taniguchi, Ishiguro: "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4." in: Journal of biochemistry, Vol. 122, Issue 3, pp. 675-80, (1998) (PubMed).

Carraway, Weber, Unger, Ledesma, Yu, Gassmann, Lai: "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." in: Nature, Vol. 387, Issue 6632, pp. 512-6, (1997) (PubMed).

Busfield, Michnick, Chickering, Revett, Ma, Woolf, Comrack, Dussault, Woolf, Goodearl, Gearing: "Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 4007-14, (1997) (PubMed).

Synonyme und alternative Namen zu Neuregulin 2

neuregulin 2 (NRG2), neuregulin 2 (Nrg2), Don1, DON1, HRG2, NRG2, NTAK, Ntak, NTAK_alpha2a

Bezeichner auf Proteinebene für Neuregulin 2

  • neuregulin 2
  • pro-NRG2
  • pro-neuregulin-2, membrane-bound isoform
  • divergent of neuregulin-1
  • neural- and thymus-derived activator for ErbB kinases
  • NTAK alpha1
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