NFASC Produkte
(Neurofascin (NFASC))
Kategorien
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009].
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Ausgewählte NFASC Kategorien
NFASC Antikörper
High quality antibodies with extensive validation data.
NFASC ELISA Kits
Reliable ELISA kits for a wide range of species.
NFASC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NFASC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (p), IF (cc), ICC, IHC (fro), IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN727325
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN3017267
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN524981
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene NFASC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958098
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN2748418
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1144672
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NFASC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7197149
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312436
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7386194
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NFASC Produkten
: "Neurofilament light chain level is a weak risk factor for the development of MS. ..." in: Neurology, Vol. 87, Issue 11, pp. 1076-84, (2016) (PubMed).: "Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures." in: ASN neuro, Vol. 6, Issue 1, pp. e00135, (2014) (PubMed).
: "Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments." in: The Journal of cell biology, Vol. 205, Issue 1, pp. 67-81, (2014) (PubMed).
: "I?B? is not required for axon initial segment assembly." in: Molecular and cellular neurosciences, Vol. 50, Issue 1, pp. 1-9, (2012) (PubMed).
: "Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis." in: Annals of neurology, Vol. 71, Issue 5, pp. 601-13, (2012) (PubMed).
: "A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly." in: Cell, Vol. 149, Issue 5, pp. 1125-39, (2012) (PubMed).
: "Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7439-53, (2012) (PubMed).
: "High-capacity peptide-centric platform to decode the proteomic response to brain injury." in: Electrophoresis, Vol. 33, Issue 24, pp. 3712-9, (2012) (PubMed).
: "Acrolein induces myelin damage in mammalian spinal cord." in: Journal of neurochemistry, Vol. 117, Issue 3, pp. 554-64, (2011) (PubMed).
: "Accumulation of Kv7.2 channels in putative ectopic transduction zones of mice nerve-end neuromas." in: Molecular pain, Vol. 7, pp. 58, (2011) (PubMed).
Synonyme und alternative Namen zu NFASC
neurofascin (NFASC), neurofascin homolog (chicken) a (nfasca), neurofascin (Nfasc), AA387016, D430023G06Rik, mKIAA0756, NF, NRCAML, sc:d0205Bezeichner auf Proteinebene für NFASC
- neurofascin
- neurofascin homolog
- neurofascin homolog (chicken)
- neurofascin-like
- neurofascin homolog (chicken) isoform 1
- neurofascin homolog (chicken) isoform 2
- neurofascin homolog (chicken) isoform 3
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