NFAT1 Produkte
(Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
Kategorien
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012].
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Ausgewählte NFAT1 Kategorien
NFAT1 Antikörper
High quality antibodies with extensive validation data.
NFAT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NFAT1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NFAT1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (2)
Kat. Nr.
ABIN6972419
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN571020
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN6748576
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NFAT1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6958239
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5657453
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NFAT1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312443
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409788
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094115
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NFAT1 Produkten
: "The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease." in: Pediatric rheumatology online journal, Vol. 18, Issue 1, pp. 23, (2020) (PubMed).: "STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension." in: Hypertension (Dallas, Tex. : 1979), Vol. 71, Issue 3, pp. 518-529, (2018) (PubMed).
: "The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB." in: International journal of molecular medicine, Vol. 40, Issue 1, pp. 155-163, (2018) (PubMed).
: "NFATc2 is an intrinsic regulator of melanoma dedifferentiation." in: Oncogene, Vol. 35, Issue 22, pp. 2862-72, (2016) (PubMed).
: "Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension." in: Experimental and therapeutic medicine, Vol. 11, Issue 2, pp. 467-475, (2016) (PubMed).
: "The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells." in: Cell death & disease, Vol. 6, pp. e1658, (2015) (PubMed).
: "Galanin modulates the neural niche to favour perineural invasion in head and neck cancer." in: Nature communications, Vol. 6, pp. 6885, (2015) (PubMed).
: "Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat." in: Circulation research, Vol. 116, Issue 10, pp. 1680-90, (2015) (PubMed).
: "NFAT targets signaling molecules to gene promoters in pancreatic β-cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 29, Issue 2, pp. 274-88, (2015) (PubMed).
: "Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein." in: Journal of virology, Vol. 88, Issue 21, pp. 12452-63, (2014) (PubMed).
Synonyme und alternative Namen zu NFAT1
nuclear factor of activated T-cells 2 (NFATC2), nuclear factor of activated T-cells 2 (nfatc2), nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2), nuclear factor of activated T-cells 2 (Nfatc2), AI607462, NF-ATc2, NFAT1, NFAT1-D, NFATC2, Nfatp, NFATPBezeichner auf Proteinebene für NFAT1
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
- nuclear factor of activated T-cells, cytoplasmic 2-like
- NF-ATp
- NFAT pre-existing subunit
- T-cell transcription factor NFAT1
- nuclear factor of activated T-cells, cytoplasmic 2
- NF-ATc2
- NFAT transcription complex, preexisting component
- T cell transcription factor NFAT1
- nuclear factor of activated T-cells, preexisting component
- preexisting nuclear factor of activated T-cells 2
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