NFATC1 Produkte
(Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
Kategorien
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2008].
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Ausgewählte NFATC1 Kategorien
NFATC1 Antikörper
High quality antibodies with extensive validation data.
NFATC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NFATC1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NFATC1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (8)
Kat. Nr.
ABIN3022101
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN686257
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IP
Validierungen
- (5)
- (3)
Kat. Nr.
ABIN967559
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene NFATC1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968983
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968984
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958238
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NFATC1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312441
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312440
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505416
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NFATC1 Produkten
: "PTPN22 interacts with EB1 to regulate T-cell receptor signaling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2020) (PubMed).: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
: "α-Linolenic Acid Inhibits Receptor Activator of NF-κB Ligand Induced (RANKL-Induced) Osteoclastogenesis and Prevents Inflammatory Bone Loss via Downregulation of Nuclear Factor-KappaB-Inducible ..." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 5056-5069, (2018) (PubMed).
: "TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways." in: Scientific reports, Vol. 6, pp. 29041, (2016) (PubMed).
: "Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate." in: International journal of oncology, Vol. 44, Issue 2, pp. 521-9, (2013) (PubMed).
: "Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1." in: Hepatology (Baltimore, Md.), Vol. 53, Issue 2, pp. 628-39, (2011) (PubMed).
: "Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling." in: The American journal of pathology, Vol. 172, Issue 1, pp. 215-24, (2008) (PubMed).
: "Autoamplification of NFATc1 expression determines its essential role in bone homeostasis." in: The Journal of experimental medicine, Vol. 202, Issue 9, pp. 1261-9, (2005) (PubMed).
: "The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production." in: Immunity, Vol. 8, Issue 1, pp. 115-24, (1998) (PubMed).
: "Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT." in: Molecular cell, Vol. 1, Issue 5, pp. 627-37, (1998) (PubMed).
Synonyme und alternative Namen zu NFATC1
nuclear factor of activated T-cells 1 (NFATC1), nuclear factor of activated T-cells 1 L homeolog (nfatc1.L), nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (nfatc1), nuclear factor of activated T-cells 1 (nfatc1), nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 (Nfatc1), nuclear factor of activated T-cells 1 (Nfatc1), 2210017P03Rik, AI449492, AV076380, nf-atc, NF-ATc, NF-ATC, NF-ATc1, NFAT, nfat2, NFAT2, nfatc, NFATc, NFATC1, Nfatcb, NFATmac, si:ch211-198c22.2Bezeichner auf Proteinebene für NFATC1
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- nuclear factor of activated T-cells, cytosolic component 1
- nuclear factor of activated T-cells calcineurin-dependent 1
- nuclear factor of activated T-cells, cytoplasmic 1
- nuclear factor of activated T-cells, cytoplasmic 1-like
- NF-ATc1
- NFAT transcription complex cytosolic component
- transcription factor NF-ATc
- NFATc
- transcription factor NFATmac
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