NFYA Produkte
(Nuclear Transcription Factor Y, alpha (NFYA))
Kategorien
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte NFYA Kategorien
NFYA Antikörper
High quality antibodies with extensive validation data.
NFYA ELISA Kits
Reliable ELISA kits for a wide range of species.
NFYA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NFYA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6257371
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN6735785
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
- (1)
Kat. Nr.
ABIN104769
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene NFYA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr.
ABIN5648500
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative DNA-Binding ELISA
Validierungen
Kat. Nr.
ABIN5526700
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NFYA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124216
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312517
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312515
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NFYA Produkten
: "p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma." in: Molecular cancer, Vol. 18, Issue 1, pp. 38, (2019) (PubMed).: "Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153658, (2016) (PubMed).
: "Regulation of the p53 transcriptional response by structurally diverse core promoters." in: Genes & development, Vol. 24, Issue 2, pp. 135-47, (2010) (PubMed).
: "Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5203-13, (2008) (PubMed).
: "NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue." in: PLoS ONE, Vol. 3, Issue 4, pp. e2047, (2008) (PubMed).
: "Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15628-37, (2008) (PubMed).
: "Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 984-94, (2008) (PubMed).
: "Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site." in: Journal of cellular physiology, Vol. 211, Issue 1, pp. 183-8, (2007) (PubMed).
: "Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4746-57, (2006) (PubMed).
: "Transcriptional modulation of the pre-implantation embryo-specific Rnf35 gene by the Y-box protein NF-Y/CBF." in: The Biochemical journal, Vol. 387, Issue Pt 2, pp. 367-75, (2005) (PubMed).
Synonyme und alternative Namen zu NFYA
nuclear transcription factor Y, alpha (nfya), nuclear transcription factor Y subunit alpha (NFYA), nuclear transcription factor-Y alpha (Nfya), nuclear transcription factor Y subunit alpha (Nfya), AA407810, CBF-A, CBF-B, Cbf-b, HAP2, ik:tdsubc_2b6, NF-YA, NFYA, SEZ-10, SEZ10, wu:fb16e03, xx:tdsubc_2b6Bezeichner auf Proteinebene für NFYA
- fb16e03
- tdsubc_2b6
- nuclear transcription factor Y, alpha
- CAAT box DNA-binding protein subunit A
- CAAT-box DNA binding protein subunit A
- CCAAT-binding transcription factor subunit B
- HAP2 CCAAT-binding protein
- Transcription factor NF-Y, A subunit
- nuclear transcription factor Y subunit A
- nuclear transcription factor Y subunit alpha
- CAAT-box DNA-binding protein subunit A
- NF-Y protein chain A
- nuclear transcription factor-Y alpha
- NF-YA
- CBF-B
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