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NFYA Produkte

(Nuclear Transcription Factor Y, alpha (NFYA))
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte NFYA Kategorien

NFYA Antikörper

High quality antibodies with extensive validation data.

NFYA ELISA Kits

Reliable ELISA kits for a wide range of species.

NFYA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NFYA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6257371
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation WB, IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN6735785
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN104769
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NFYA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr. ABIN5648500
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validierungen
Kat. Nr. ABIN5526700
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NFYA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124216
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312517
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312515
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NFYA Produkten

Jin, Yang, Li, Yang, Ma, Zhang: "p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma." in: Molecular cancer, Vol. 18, Issue 1, pp. 38, (2019) (PubMed).

Falcone, Grandoni, Garibaldi, Manni, Filligoi, Piaggio, Gurtner: "Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153658, (2016) (PubMed).

Morachis, Murawsky, Emerson: "Regulation of the p53 transcriptional response by structurally diverse core promoters." in: Genes & development, Vol. 24, Issue 2, pp. 135-47, (2010) (PubMed).

Manni, Caretti, Artuso, Gurtner, Emiliozzi, Sacchi, Mantovani, Piaggio: "Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5203-13, (2008) (PubMed).

Gurtner, Fuschi, Magi, Colussi, Gaetano, Dobbelstein, Sacchi, Piaggio: "NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue." in: PLoS ONE, Vol. 3, Issue 4, pp. e2047, (2008) (PubMed).

Bennett, Seo, Datta, Shin, Osborne: "Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15628-37, (2008) (PubMed).

Chia, Leung, Krushel, Alajez, Lo, Busson, Klamut, Bastianutto, Liu: "Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 984-94, (2008) (PubMed).

Paradkar, Roth: "Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site." in: Journal of cellular physiology, Vol. 211, Issue 1, pp. 183-8, (2007) (PubMed).

Cecchinelli, Lavra, Rinaldo, Iacovelli, Gurtner, Gasbarri, Ulivieri, Del Prete, Trovato, Piaggio, Bartolazzi, Soddu, Sciacchitano: "Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4746-57, (2006) (PubMed).

Huang, Wu, Choo: "Transcriptional modulation of the pre-implantation embryo-specific Rnf35 gene by the Y-box protein NF-Y/CBF." in: The Biochemical journal, Vol. 387, Issue Pt 2, pp. 367-75, (2005) (PubMed).

Synonyme und alternative Namen zu NFYA

nuclear transcription factor Y, alpha (nfya), nuclear transcription factor Y subunit alpha (NFYA), nuclear transcription factor-Y alpha (Nfya), nuclear transcription factor Y subunit alpha (Nfya), AA407810, CBF-A, CBF-B, Cbf-b, HAP2, ik:tdsubc_2b6, NF-YA, NFYA, SEZ-10, SEZ10, wu:fb16e03, xx:tdsubc_2b6

Bezeichner auf Proteinebene für NFYA

  • fb16e03
  • tdsubc_2b6
  • nuclear transcription factor Y, alpha
  • CAAT box DNA-binding protein subunit A
  • CAAT-box DNA binding protein subunit A
  • CCAAT-binding transcription factor subunit B
  • HAP2 CCAAT-binding protein
  • Transcription factor NF-Y, A subunit
  • nuclear transcription factor Y subunit A
  • nuclear transcription factor Y subunit alpha
  • CAAT-box DNA-binding protein subunit A
  • NF-Y protein chain A
  • nuclear transcription factor-Y alpha
  • NF-YA
  • CBF-B
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