Nibrin Produkte
(Nibrin (NBN))
Kategorien
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008].
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Ausgewählte Nibrin Kategorien
Nibrin Antikörper
High quality antibodies with extensive validation data.
Nibrin ELISA Kits
Reliable ELISA kits for a wide range of species.
Nibrin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Nibrin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN1724942
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN1724946
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p)
Validierungen
- (9)
Kat. Nr.
ABIN1491539
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Nibrin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380647
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380503
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1145103
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Nibrin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312044
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1989706
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396661
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Nibrin Produkten
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
: "Identification of a novel NBN truncating mutation in a family with hereditary prostate cancer." in: Familial cancer, Vol. 11, Issue 4, pp. 595-600, (2012) (PubMed).
: "Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells." in: Cancer prevention research (Philadelphia, Pa.), Vol. 4, Issue 12, pp. 1973-81, (2011) (PubMed).
: "Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma." in: Molecular carcinogenesis, Vol. 50, Issue 9, pp. 689-96, (2011) (PubMed).
: "Prominent oromandibular dystonia and pharyngeal telangiectasia in atypical ataxia telangiectasia." in: Cerebellum (London, England), Vol. 8, Issue 1, pp. 22-7, (2009) (PubMed).
: "Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 42, pp. 16165-70, (2008) (PubMed).
: "Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells." in: Cancer research, Vol. 67, Issue 4, pp. 1513-9, (2007) (PubMed).
: "Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype." in: Cancer research, Vol. 66, Issue 6, pp. 2907-12, (2006) (PubMed).
: "Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition." in: Cancer research, Vol. 66, Issue 16, pp. 8109-15, (2006) (PubMed).
Synonyme und alternative Namen zu Nibrin
nibrin (NBN), nibrin (nbn), nibrin (Nbn), AT-V1, AT-V2, ATV, im:6911679, NBN, NBS, NBS1, Nbs1, P95, zgc:194152Bezeichner auf Proteinebene für Nibrin
- nibrin
- Nijmegen breakage syndrome 1 (nibrin)
- cell cycle regulatory protein p95
- p95 protein of the MRE11/RAD50 complex
- nijmegen breakage syndrome protein 1 homolog
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