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NIPBL Produkte

(Nipped-B like Protein (NIPBL))

Kategorien

This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte NIPBL Kategorien

NIPBL Antikörper

High quality antibodies with extensive validation data.

NIPBL Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NIPBL Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
  • (1)
Kat. Nr. ABIN1714202
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN570861
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7161618
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NIPBL ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6205160
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NIPBL Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312586
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312588
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NIPBL Produkten

Mazzola, Deflorian, Pezzotta, Ferrari, Fazio, Bresciani, Saitta, Ferrari, Fumagalli, Parma, Marasca, Bodega, Riva, Cotelli, Biondi, Marozzi, Cazzaniga, Pistocchi: "NIPBL: a new player in myeloid cell differentiation." in: Haematologica, Vol. 104, Issue 7, pp. 1332-1341, (2019) (PubMed).

Xu, Ying, Shan, Feng, Zhang, Gao, Xu, Yao, Zhu, Mao: "Enhanced expression of cohesin loading factor NIPBL confers poor prognosis and chemotherapy resistance in non-small cell lung cancer." in: Journal of translational medicine, Vol. 13, pp. 153, (2015) (PubMed).

Liu, Zhang, Bando, Itoh, Deardorff, Clark, Kaur, Tandy, Kondoh, Rappaport, Spinner, Vega, Jackson, Shirahige, Krantz: "Transcriptional dysregulation in NIPBL and cohesin mutant human cells." in: PLoS biology, Vol. 7, Issue 5, pp. e1000119, (2009) (PubMed).

Seitan, Banks, Laval, Majid, Dorsett, Rana, Smith, Bateman, Krpic, Hostert, Rollins, Erdjument-Bromage, Tempst, Benard, Hekimi, Newbury, Strachan: "Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance." in: PLoS biology, Vol. 4, Issue 8, pp. e242, (2006) (PubMed).

Synonyme und alternative Namen zu NIPBL

NIPBL, cohesin loading factor (NIPBL), Nipped-B homolog-like (NIPBLL), NIPBL, cohesin loading factor S homeolog (nipbl.S), Nipped-B homolog-like (LOC427439), nipped-B homolog b (Drosophila) (nipblb), nipped-B-like protein A (LOC100164947), NIPBL, cohesin loading factor (nipbl), Nipped-B homolog (Drosophila) (Nipbl), NIPBL, cohesin loading factor (Nipbl), 4921518A06Rik, 4933421G18Rik, C79399, CDLS, CDLS1, IDN3, Idn3, IDN3-B, nipbl, NIPBL, nipbla, Scc2, scc2, scc2-2, SCC2W, wu:fi33d08

Bezeichner auf Proteinebene für NIPBL

  • SCC2 homolog
  • delangin
  • nipped-B-like protein
  • sister chromatid cohesion 2 homolog
  • Nipped-B homolog
  • Scc2-2A
  • Scc2-2B
  • sister chromatid cohesion establishment factor 2
  • Nipped-B homolog (Drosophila)
  • nipped-B like a
  • nipped-B-like protein B
  • nipped-B-like protein-like
  • delangin homolog
  • LOW QUALITY PROTEIN: nipped-B-like protein
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