NLRC4 Produkte
(NLR Family, CARD Domain Containing 4 (NLRC4))
Kategorien
In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM, Mar 2008].
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Ausgewählte NLRC4 Kategorien
NLRC4 Antikörper
High quality antibodies with extensive validation data.
NLRC4 ELISA Kits
Reliable ELISA kits for a wide range of species.
NLRC4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NLRC4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7008065
Menge
60 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, ICC
Validierungen
- (4)
Kat. Nr.
ABIN5611209
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
Kat. Nr.
ABIN6144657
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NLRC4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968953
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962707
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958209
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NLRC4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124183
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312662
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094174
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NLRC4 Produkten
: "Iraqi propolis increases degradation of IL-1β and NLRC4 by autophagy following Pseudomonas aeruginosa infection." in: Microbes and infection, Vol. 20, Issue 2, pp. 89-100, (2018) (PubMed).: "Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121525, (2015) (PubMed).
: "Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation." in: American journal of physiology. Renal physiology, Vol. 306, Issue 3, pp. F299-308, (2014) (PubMed).
: "Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization." in: Immunity, Vol. 37, Issue 1, pp. 35-47, (2012) (PubMed).
: "A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif." in: Nature cell biology, Vol. 2, Issue 12, pp. 915-21, (2001) (PubMed).
: "Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2." in: Gene, Vol. 261, Issue 2, pp. 197-203, (2001) (PubMed).
: "Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1." in: The Journal of biological chemistry, Vol. 276, Issue 30, pp. 28309-13, (2001) (PubMed).
: "Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis." in: Biochemical and biophysical research communications, Vol. 284, Issue 1, pp. 77-82, (2001) (PubMed).
: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).
: "Apoptosis. Till death us do part." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).
Synonyme und alternative Namen zu NLRC4
NLR family CARD domain containing 4 (NLRC4), NLR family, CARD domain containing 4 (Nlrc4), 9530011P19Rik, CARD12, Card12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAFBezeichner auf Proteinebene für NLRC4
- caspase recruitment domain protein 12
- NLR family CARD domain-containing protein 4
- ice protease-activating factor
- ipaf
- NLR family, CARD domain containing 4
- CARD, LRR, and NACHT-containing protein
- ICE-protease activating factor
- NOD-like receptor C4
- caspase recruitment domain family, member 12
- caspase recruitment domain-containing protein 12
- nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
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