Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

NLRP3 Produkte

(NLR Family, Pyrin Domain Containing 3 (NLRP3))

Kategorien

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq, Oct 2008].

antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.

Ausgewählte NLRP3 Kategorien

NLRP3 Antikörper

High quality antibodies with extensive validation data.

NLRP3 ELISA Kits

Reliable ELISA kits for a wide range of species.

NLRP3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NLRP3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC, IF, IP
Validierungen
  • (60)
  • (5)
Kat. Nr. ABIN1169100
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Dog, Human, Mouse, Rat
Applikation WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validierungen
  • (11)
  • (15)
Kat. Nr. ABIN1386361
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7443710
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NLRP3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971279
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958211
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958210
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NLRP3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN1312675
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124184
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312677
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NLRP3 Produkten

Qu, Fan, Qi, Xu, Hu, Chen, Liu, Liu, Si: "Akkermansia muciniphila Alleviates Dextran Sulfate Sodium (DSS)-Induced Acute Colitis by NLRP3 Activation." in: Microbiology spectrum, Vol. 9, Issue 2, pp. e0073021, (2022) (PubMed).

Lv, Liu, Ye, Yang, Duan, Yao, Li, Tang, Chen, Liu, Deng, Wang, Xing, Liang, Xu, Ye: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).

An, Zhang, Cao, Chen, Qin, Yang: "Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway." in: Nutrients, Vol. 12, Issue 5, (2021) (PubMed).

Li, Jiang, Ye, Zhou, Liu, Yang, Hao, Hu: "P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages." in: Cell death & disease, Vol. 11, Issue 5, pp. 394, (2021) (PubMed).

Zhou, Xiao, Zhao, Tan, Long, Yu, He: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).

Wu, Pan, Luo, Shen, Meng, Xiao, Tan, Nie, Tong, Wang: "Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis." in: Molecular medicine reports, Vol. 22, Issue 4, pp. 2695-2704, (2021) (PubMed).

Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

Zhu, Tang: "LncRNA Gm14205 induces astrocytic NLRP3 inflammasome activation via inhibiting oxytocin receptor in postpartum depression." in: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).

Wong, Lewis, Doherty, Shi, Cashikar, Amelianchik, Tymchuk, Sullivan, Qian, Covey, Petsko, Holtzman, Paul, Luo: "25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner." in: Journal of neuroinflammation, Vol. 17, Issue 1, pp. 192, (2020) (PubMed).

Hoyle, Redondo-Castro, Cook, Tzeng, Allan, Brough, Lemarchand: "Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture." in: Immunology, Vol. 161, Issue 1, pp. 39-52, (2020) (PubMed).

Synonyme und alternative Namen zu NLRP3

NLR family pyrin domain containing-like (NLRPL), NLR family pyrin domain containing 3 (NLRP3), NLR family, pyrin domain containing 3 L homeolog (nlrp3.L), NLR family, pyrin domain containing 3 (Nlrp3), agtavprl, AGTAVPRL, AII, AII/AVP, avp, AVP, C1orf7, CIAS1, cias1, Cias1, CLR1.1, FCAS, FCU, Mmig1, MWS, Nalp3, nalp3, NALP3, pypaf1, PYPAF1, Pypaf1

Bezeichner auf Proteinebene für NLRP3

  • NACHT, LRR and PYD domains-containing protein 3
  • cold autoinflammatory syndrome 1
  • cryopyrin
  • NLR family, pyrin domain containing 3
  • NACHT, LRR and PYD domains-containing protein 3-like
  • NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3
  • NACHT, LRR and PYD containing protein 3
  • PYRIN-containing APAF1-like protein 1
  • caterpiller protein 1.1
  • cold autoinflammatory syndrome 1 protein
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
  • NACHT/LRR/pyrin domain-containing protein 3
  • cold autoinflammatory syndrome 1 homolog
  • cold autoinflammatory syndrome 1 protein homolog
  • mast cell maturation inducible protein 1
  • mast cell maturation-associated-inducible protein 1
  • NLR family pyrin domain containing 3
Sie sind hier:
Kundenservice