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NOTCH3 Produkte

(Notch 3 (NOTCH3))
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008].

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Ausgewählte NOTCH3 Kategorien

NOTCH3 Antikörper

High quality antibodies with extensive validation data.

NOTCH3 ELISA Kits

Reliable ELISA kits for a wide range of species.

NOTCH3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NOTCH3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN7074862
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IF, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN390159
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN3023484
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NOTCH3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968971
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968972
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958226
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NOTCH3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275361
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275362
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275366
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NOTCH3 Produkten

Diéguez-Hurtado, Kato, Giaimo, Nieminen-Kelhä, Arf, Ferrante, Bartkuhn, Zimmermann, Bixel, Eilken, Adams, Borggrefe, Vajkoczy, Adams: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." in: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).

Kato, Diéguez-Hurtado, Park, Hong, Kato-Azuma, Adams, Stehling, Trappmann, Wrana, Koh, Adams: "Pulmonary pericytes regulate lung morphogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).

Zhang, Dong, Wang, Wang, Chen, Huang: "Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 2538-2546, (2017) (PubMed).

Liu, Yang, Wang, Miao, Liu, Li, Zou, Li, Liang, Zeng, Chen: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." in: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).

Zhou, Jiang, Dong, Yan, You, Su, Gong: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." in: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).

Soylu, Acar, Ozbey, Unal, Koksal, Bassorgun, Ciftcioglu, Ustunel: "Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma." in: Pathology oncology research : POR, Vol. 22, Issue 1, pp. 87-94, (2015) (PubMed).

Ehret, Vogler, Pojar, Elliott, Bradke, Steiner, Kempermann: "Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis." in: Neurobiology of disease, Vol. 75, pp. 131-41, (2015) (PubMed).

Rusanescu, Mao: "Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord." in: Journal of cellular and molecular medicine, Vol. 18, Issue 10, pp. 2103-16, (2014) (PubMed).

Soriani, Iannitto, Ricci, Fionda, Malgarini, Morrone, Peruzzi, Ricciardi, Petrucci, Cippitelli, Santoni: "Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 950-60, (2014) (PubMed).

Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).

Synonyme und alternative Namen zu NOTCH3

notch 3 (NOTCH3), notch 3 (Notch3), notch 3 (notch3), AW229011, CADASIL, CASIL, fa14b08, hpbk, IMF2, N3, notch5, wu:fa14b08

Bezeichner auf Proteinebene für NOTCH3

  • Notch homolog 3
  • neurogenic locus notch homolog protein 3
  • Notch gene homolog 3
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