NOXA Produkte
(Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
Kategorien
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
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Ausgewählte NOXA Kategorien
NOXA Antikörper
High quality antibodies with extensive validation data.
NOXA ELISA Kits
Reliable ELISA kits for a wide range of species.
NOXA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NOXA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN6145810
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN7193484
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7163088
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene NOXA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969250
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969249
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Validierungen
Kat. Nr.
ABIN1147675
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NOXA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315507
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3130350
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2727491
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NOXA Produkten
: "Genome-scale CRISPR screening for potential targets of ginsenoside compound K." in: Cell death & disease, Vol. 11, Issue 1, pp. 39, (2021) (PubMed).: "HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma." in: International journal of cancer, Vol. 142, Issue 9, pp. 1926-1937, (2019) (PubMed).
: "Targeting prosurvival BCL2 signaling through Akt blockade sensitizes castration-resistant prostate cancer cells to enzalutamide." in: The Prostate, Vol. 79, Issue 11, pp. 1347-1359, (2019) (PubMed).
: "Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia." in: Cancer research, Vol. 78, Issue 20, pp. 5793-5807, (2018) (PubMed).
: "Mannose impairs tumour growth and enhances chemotherapy." in: Nature, Vol. 563, Issue 7733, pp. 719-723, (2018) (PubMed).
: "Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins." in: Oncogene, Vol. 36, Issue 35, pp. 4953-4962, (2017) (PubMed).
: "Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice." in: Cell death & disease, Vol. 8, Issue 1, pp. e2556, (2017) (PubMed).
: "Bax/Bak activation in the absence of Bid, Bim, Puma, and p53." in: Cell death & disease, Vol. 7, pp. e2266, (2016) (PubMed).
: "p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death." in: Oncogene, (2015) (PubMed).
: "Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner." in: Gut, Vol. 64, Issue 7, pp. 1040-8, (2015) (PubMed).
Synonyme und alternative Namen zu NOXA
phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1), phorbol-12-myristate-13-acetate-induced protein 1 (pmaip1), phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1), APR, NOXA, Noxa, PMAIP1, TN3, zgc:162379Bezeichner auf Proteinebene für NOXA
- phorbol-12-myristate-13-acetate-induced protein 1
- Noxa
- PMA-induced protein 1
- adult T cell leukemia-derived PMA-responsive
- immediate-early-response protein APR
- protein Noxa
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