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NPC2 Produkte

(Niemann-Pick Disease, Type C2 (NPC2))

Kategorien

This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008].

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Ausgewählte NPC2 Kategorien

NPC2 Antikörper

High quality antibodies with extensive validation data.

NPC2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NPC2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NPC2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7261367
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (4)
Kat. Nr. ABIN524004
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN524003
Menge 50 μg
Datenblatt Datenblatt

Empfohlene NPC2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958196
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951621
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951622
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NPC2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312853
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312851
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7321066
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NPC2 Produkten

Giacomini, Ura, Giolo, Luppi, Martinelli, Garcia, Ricci: "Comparative analysis of the seminal plasma proteomes of oligoasthenozoospermic and normozoospermic men." in: Reproductive biomedicine online, Vol. 30, Issue 5, pp. 522-31, (2015) (PubMed).

Roszell, Tao, Yu, Gao, Huang, Ning, Feinstein, Vite, Bates: "Pulmonary abnormalities in animal models due to Niemann-Pick type C1 (NPC1) or C2 (NPC2) disease." in: PLoS ONE, Vol. 8, Issue 7, pp. e67084, (2013) (PubMed).

Taguchi, Politi, Pitteri, Lockwood, Faça, Kelly-Spratt, Wong, Zhang, Chin, Park, Goodman, Gazdar, Sage, Dinulescu, Kucherlapati, Depinho, Kemp, Varmus, Hanash: "Lung cancer signatures in plasma based on proteome profiling of mouse tumor models." in: Cancer cell, Vol. 20, Issue 3, pp. 289-99, (2011) (PubMed).

Pernemalm, De Petris, Eriksson, Brandén, Koyi, Kanter, Lewensohn, Lehtiö: "Use of narrow-range peptide IEF to improve detection of lung adenocarcinoma markers in plasma and pleural effusion." in: Proteomics, Vol. 9, Issue 13, pp. 3414-24, (2009) (PubMed).

Xu, Farver, Kodukula, Storch: "Regulation of sterol transport between membranes and NPC2." in: Biochemistry, Vol. 47, Issue 42, pp. 11134-43, (2008) (PubMed).

Infante, Radhakrishnan, Abi-Mosleh, Kinch, Wang, Grishin, Goldstein, Brown: "Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop." in: The Journal of biological chemistry, Vol. 283, Issue 2, pp. 1064-75, (2008) (PubMed).

Infante, Wang, Radhakrishnan, Kwon, Brown, Goldstein: "NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 40, pp. 15287-92, (2008) (PubMed).

Légaré, Thabet, Gatti, Sullivan: "HE1/NPC2 status in human reproductive tract and ejaculated spermatozoa: consequence of vasectomy." in: Molecular human reproduction, Vol. 12, Issue 7, pp. 461-8, (2006) (PubMed).

Synonyme und alternative Namen zu NPC2

NPC intracellular cholesterol transporter 2 (Npc2), NPC intracellular cholesterol transporter 2 (NPC2), Niemann-Pick disease, type C2 (npc2), 2700012J19Rik, AA408070, AU045843, cb292, CE1, EDDM1, EPI-1, HE1, re1, sb:cb292

Bezeichner auf Proteinebene für NPC2

  • epididymal secretory protein E1
  • mE1
  • niemann Pick type C2 protein homolog
  • Niemann-Pick disease type C2 protein
  • epididymal protein 1
  • human epididymis-specific protein 1
  • tissue-specific secretory protein
  • Niemann Pick type C2
  • epididymal secretory protein 1
  • EPV20
  • 16 kDa secretory protein
  • 16kDa secretory protein
  • 16.5 kDa secretory protein
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