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NPTX2 Produkte

(Neuronal Pentraxin II (NPTX2))

Kategorien

This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009].

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Ausgewählte NPTX2 Kategorien

NPTX2 Antikörper

High quality antibodies with extensive validation data.

NPTX2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NPTX2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NPTX2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN6242482
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN389175
Menge 400 μL
Datenblatt Datenblatt

Applikation WB
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6746446
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NPTX2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958131
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958132
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958133
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NPTX2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312904
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7410661
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7389926
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NPTX2 Produkten

Goetzl, Abner, Jicha, Kapogiannis, Schwartz: "Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 2, pp. 888-893, (2018) (PubMed).

Shukla, Pia Patric, Thinagararjan, Srinivasan, Mondal, Hegde, Chandramouli, Santosh, Arivazhagan, Somasundaram: "A DNA methylation prognostic signature of glioblastoma: identification of NPTX2-PTEN-NF-κB nexus." in: Cancer research, Vol. 73, Issue 22, pp. 6563-73, (2013) (PubMed).

Moran, Hickey, Michael, Derkacs, Christian, Kalaitzakis, Pearce, Graeber: "Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies." in: Acta neuropathologica, Vol. 115, Issue 4, pp. 471-8, (2008) (PubMed).

Marui, Koishi, Funatogawa, Yamamoto, Matsumoto, Hashimoto, Ishijima, Nanba, Nishida, Sugiyama, Kasai, Watanabe, Kano, Kato, Sasaki: "No association between the neuronal pentraxin II gene polymorphism and autism." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 31, Issue 4, pp. 940-3, (2007) (PubMed).

Park, Ryu, Lee, Lee, Yoon, Lee, Yoo, Woo, Lee, Lee, Kim, Yoon: "Quantitative analysis of NPTX2 hypermethylation is a promising molecular diagnostic marker for pancreatic cancer." in: Pancreas, Vol. 35, Issue 3, pp. e9-15, (2007) (PubMed).

Xu, Hopf, Reddy, Cho, Guo, Lanahan, Petralia, Wenthold, OBrien, Worley: "Narp and NP1 form heterocomplexes that function in developmental and activity-dependent synaptic plasticity." in: Neuron, Vol. 39, Issue 3, pp. 513-28, (2003) (PubMed).

Wong, Setou, Teng, Takei, Hirokawa: "Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14500-5, (2002) (PubMed).

Biederer, Südhof: "Mints as adaptors. Direct binding to neurexins and recruitment of munc18." in: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39803-6, (2001) (PubMed).

Kirkpatrick, Matzuk, Dodds, Perin: "Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17786-92, (2000) (PubMed).

Tsui, Copeland, Gilbert, Jenkins, Barnes, Worley: "Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 8, pp. 2463-78, (1996) (PubMed).

Synonyme und alternative Namen zu NPTX2

neuronal pentraxin 2 (NPTX2), neuronal pentraxin 2 (Nptx2), neuronal pentraxin II (NPTX2), neuronal pentraxin 1 (NPTX1), neuronal pentraxin 2a (nptx2a), NARP, Narp, NP-II, NP2, np2, NPTX2, nptx2, p50

Bezeichner auf Proteinebene für NPTX2

  • apexin
  • neuronal activity-regulated pentaxin
  • neuronal pentraxin-2
  • NP-II
  • neuro activity regulated petaxin
  • neuronal pentraxin II
  • NP2
  • neuronal activity-regulated pentraxin
  • neuronal pentraxin 2
  • AM50
  • acrosomal pentaxin-like protein p50
  • narp
  • neuronal pentraxin 2a
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