NR0B2 Produkte
(Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
Kategorien
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008].
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Ausgewählte NR0B2 Kategorien
NR0B2 Antikörper
High quality antibodies with extensive validation data.
NR0B2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NR0B2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NR0B2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (5)
Kat. Nr.
ABIN3015601
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, FACS, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN655027
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Monkey, Rabbit
Applikation
WB, IHC, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN6741607
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NR0B2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958250
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN627370
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN995938
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NR0B2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312927
Menge
2 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7413040
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7418809
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NR0B2 Produkten
: "Bile acid malabsorption is associated with diarrhea in acute phase of colitis." in: Canadian journal of physiology and pharmacology, Vol. 96, Issue 12, pp. 1328-1336, (2019) (PubMed).: "Raspberry pomace alters cecal microbial activity and reduces secondary bile acids in rats fed a high-fat diet." in: The Journal of nutritional biochemistry, Vol. 46, pp. 13-20, (2017) (PubMed).
: "The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3)." in: Molecular pharmacology, Vol. 82, Issue 5, pp. 918-28, (2012) (PubMed).
: "Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth." in: Gastroenterology, Vol. 134, Issue 3, pp. 793-802, (2008) (PubMed).
: "Cellular distributions of molecules with altered expression specific to the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model." in: Carcinogenesis, Vol. 29, Issue 11, pp. 2218-26, (2008) (PubMed).
: "Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 10, pp. 2326-42, (2006) (PubMed).
Synonyme und alternative Namen zu NR0B2
nuclear receptor subfamily 0 group B member 2 (NR0B2), nuclear receptor subfamily 0, group B, member 2 (Nr0b2), nuclear receptor subfamily 0, group B, member 2a (nr0b2a), gb:bc058069, Nr0b2, NR0B2-A, SHP, Shp, SHP-1, SHP-A, SHP1, Shp1Bezeichner auf Proteinebene für NR0B2
- short heterodimer partner
- nuclear receptor subfamily 0 group B member 2
- nuclear receptor SHP
- orphan nuclear receptor SHP
- small heterodimer partner
- small heterodimer partner homologue
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